2XIJ

Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin

エンティティ

Entity ID	鎖名	説明	種類	鎖長	化学式量	分子数	データベース名(アクセス番号)	由来する生物種	エンティティの一般名
1	A	METHYLMALONYL-COA MUTASE, MITOCHONDRIAL	polymer	762	84835.8	1	UniProt (P22033) Pfam (PF01642) Pfam (PF02310) In PDB	HOMO SAPIENS (HUMAN)	MCM, METHYLMALONYL-COA ISOMERASE
2	A	5'-DEOXYADENOSINE	non-polymer		251.2	1	Chemie (5AD)
3	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
5	A	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
6	A	COBALAMIN	non-polymer		1330.4	1	Chemie (B12)
7		water	water		18.0	528	Chemie (HOH)

配列変更

A: 12 - 750 (UniProt: P22033)

PDB	外部データベース	詳細
Met 11	-	expression tag
Ala 751	-	expression tag
Glu 752	-	expression tag
Asn 753	-	expression tag
Leu 754	-	expression tag
Tyr 755	-	expression tag
Phe 756	-	expression tag
Gln 757	-	expression tag
Ser 758	-	expression tag
His 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag
His 762	-	expression tag
His 763	-	expression tag
His 764	-	expression tag
Asp 765	-	expression tag
Tyr 766	-	expression tag
Lys 767	-	expression tag
Asp 768	-	expression tag
Asp 769	-	expression tag
Asp 770	-	expression tag
Asp 771	-	expression tag
Lys 772	-	expression tag
Thr 499	Ala 499	variant

非対称単位の内容

タンパク質・ 核酸鎖	鎖の数	1
	化学式量合計	84835.8
タンパク質・ 核酸・ 糖鎖以外*	分子数	13
	化学式量合計	2479.5
全て*	化学式量合計	87315.3

*水分子は含んでいません