2XAE
Crystal structure of human kinesin Eg5 in complex with (R)-2-amino-3-((S)-2-methyl-1,1-diphenylbutylthio)propanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 3 | UniProt (P52732) Pfam (PF00225) In PDB | HOMO SAPIENS (HUMAN) | EG5, KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5, KINESIN-LIKE PROTEIN 1 |
| 2 | A, B, C | (2R)-2-AMINO-3-[(4-CHLOROPHENYL)-DIPHENYL-METHYL]SULFANYL-PROPANOIC ACID | non-polymer | 397.9 | 3 | Chemie (2XA) | |||
| 3 | A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | A, B, C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | B, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123166.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2871.9 | |
| All* | Total formula weight | 126038.7 |
