2X7E

Crystal structure of human kinesin Eg5 in complex with (R)-fluorastrol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	KINESIN-LIKE PROTEIN KIF11	polymer	368	41055.6	2	UniProt (P52732) Pfam (PF00225) In PDB	HOMO SAPIENS (HUMAN)	KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, KINESIN-LIKE PROTEIN 1, TRIP-5
2	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	(4R)-5-[(S)-(3,4-DIFLUOROPHENYL)(HYDROXY)METHYL]-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-3,4-DIHYDROPYRIMIDINE-2(1H)-THIONE	non-polymer		376.4	2	Chemie (X7E)
5		water	water		18.0	336	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	82111.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1655.9
All*	Total formula weight	83767.0

*Water molecules are not included.