2OJG
Crystal structure of ERK2 in complex with N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
エンティティ
| Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
| 1 | A | Mitogen-activated protein kinase 1 | polymer | 380 | 43616.0 | 1 | UniProt (P28482) Pfam (PF00069) In PDB | Homo sapiens (human) | Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, p42-MAPK, ERT1 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE | non-polymer | 280.3 | 1 | Chemie (19A) | |||
| 4 | water | water | 18.0 | 188 | Chemie (HOH) |
配列変更
A: 0 - 358 (UniProt: P28482)
| PDB | 外部データベース | 詳細 |
|---|---|---|
| Met -21 | - | cloning artifact |
| Gly -20 | - | cloning artifact |
| Ser -19 | - | cloning artifact |
| Ser -18 | - | cloning artifact |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| Ser -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| Gly -9 | - | cloning artifact |
| Leu -8 | - | cloning artifact |
| Val -7 | - | cloning artifact |
| Pro -6 | - | cloning artifact |
| Arg -5 | - | cloning artifact |
| Gly -4 | - | cloning artifact |
| Ser -3 | - | cloning artifact |
| His -2 | - | cloning artifact |
| Met -1 | - | cloning artifact |
配列ビューア
非対称単位の内容
| タンパク質・ 核酸鎖 | 鎖の数 | 1 |
| 化学式量合計 | 43616.0 | |
| タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 2 |
| 化学式量合計 | 376.4 | |
| 全て* | 化学式量合計 | 43992.4 |
