2FL2
crystal structure of KSP in complex with inhibitor 19
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Kinesin-like protein KIF11 | polymer | 367 | 40924.4 | 2 | UniProt (P52732) Pfam (PF00225) In PDB | Homo sapiens (human) | Kinesin-related motor protein Eg5, Kinesin-like spindle protein HKSP, Thyroid receptor interacting protein 5, TRIP5, Kinesin-like protein 1 |
2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
4 | A, B | (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE | non-polymer | 354.4 | 2 | Chemie (N4T) | |||
5 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 81848.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1611.8 | |
All* | Total formula weight | 83460.6 |