1ZCM
Human calpain protease core inhibited by ZLLYCH2F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Calpain 1, large [catalytic] subunit | polymer | 321 | 36364.0 | 1 | UniProt (P07384) Pfam (PF00648) In PDB | Homo sapiens (human) | Calcium-activated neutral proteinase, CANP, Mu-type, muCANP, Micromolar-calpain |
| 2 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | A | N-[(BENZYLOXY)CARBONYL]LEUCYL-N~1~-[3-FLUORO-1-(4-HYDROXYBENZYL)-2-OXOPROPYL]LEUCINAMIDE | non-polymer | 557.7 | 1 | Chemie (C1N) | |||
| 4 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 33 - 353 (UniProt: P07384)
| PDB | External Database | Details |
|---|---|---|
| Ala 213 | Gly 213 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36364.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 637.8 | |
| All* | Total formula weight | 37001.8 |
