1YXX

Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proto-oncogene serine/threonine-protein kinase Pim-1	polymer	293	33832.3	1	UniProt (P11309) Pfam (PF00069) In PDB	Homo sapiens (human)
2	A	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
3	A	(3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE	non-polymer		238.2	1	Chemie (LI7)
4		water	water		18.0	105	Chemie (HOH)

Sequence modifications

A: 29 - 313 (UniProt: P11309)

PDB	External Database	Details
Val 314	-	expression tag
Asp 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33832.3
Non-Polymers*	Number of molecules	2
	Total formula weight	307.3
All*	Total formula weight	34139.6

*Water molecules are not included.