1W8P
Structural properties of the B25Tyr-NMe-B26Phe insulin mutant.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... | INSULIN A-CHAIN | polymer | 21 | 2383.7 | 6 | UniProt (P01308) In PDB | HOMO SAPIENS | |
| 2 | B, D, F, H, J... | INSULIN B-CHAIN | polymer | 30 | 3434.0 | 6 | UniProt (P01308) Pfam (PF00049) In PDB | HOMO SAPIENS | |
| 3 | A, C, E, G, I... | PHENOL | non-polymer | 94.1 | 6 | Chemie (IPH) | |||
| 4 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
B, D, F, H, J, L: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Tyr 25 | Phe 49 | engineered mutation |
| Phe 26 | Tyr 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 34905.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 695.5 | |
| All* | Total formula weight | 35601.4 |
