1W1I
Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase
エンティティ
| Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
| 1 | A, B, C, D | DIPEPTIDYL PEPTIDASE IV | polymer | 728 | 84462.6 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) In PDB | HOMO SAPIENS (HUMAN) | DPP IV, T-CELL ACTIVATION ANTIGEN CD26, TP103, ADENOSINE DEAMINASE COMPLEXING PROTEIN-2, ADABP |
| 2 | E, F, G, H | ADENOSINE DEAMINASE | polymer | 357 | 40457.9 | 4 | UniProt (P56658) Pfam (PF00962) In PDB | BOS TAURUS (BOVINE) | ADENOSINE AMINOHYDROLASE |
| 3 | I, Q | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 4 | J, K, N, P, R... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 5 | L, O, T, X | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 4 | In PDB GlyTouCan (G81315DD) | |||
| 6 | M, V | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 7 | A, B, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
| 8 | E, F, G, H | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
配列変更
E, F, G, H: 1 - 357 (UniProt: P56658)
| PDB | 外部データベース | 詳細 |
|---|---|---|
| Asp 8 | Asn 7 | conflict |
| Lys 32 | Arg 31 | conflict |
| Arg 33 | Lys 32 | conflict |
| Leu 47 | Gln 46 | conflict |
| Thr 57 | Ser 56 | conflict |
| Asp 60 | Glu 59 | conflict |
| Asp 77 | Glu 76 | conflict |
| Ile 79 | Val 78 | conflict |
| Gln 199 | Lys 198 | variant |
| Thr 246 | Ala 245 | variant |
| Ile 261 | Val 260 | conflict |
| Ala 279 | Pro 278 | conflict |
| Ile 281 | Val 280 | conflict |
| Lys 313 | Asn 312 | conflict |
| Asp 314 | Glu 313 | conflict |
| Arg 352 | Gly 351 | variant |
配列ビューア
非対称単位の内容
| タンパク質・ 核酸鎖 | 鎖の数 | 8 |
| 化学式量合計 | 499682.1 | |
| 糖鎖 | 分子数 | 17 |
| 化学式量合計 | 8690.1 | |
| タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 19 |
| 化学式量合計 | 3579.8 | |
| 全て* | 化学式量合計 | 511951.9 |
