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1OIT

Imidazopyridines: a potent and selective class of Cyclin-dependent Kinase inhibitors identified through Structure-based hybridisation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACELL DIVISION PROTEIN KINASE 2polymer29934018.51UniProt (P24941)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)P33 PROTEIN KINASE
2A4-[(4-IMIDAZO[1,2-A]PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]BENZENESULFONAMIDEnon-polymer366.41Chemie (HDT)
3waterwater18.0194Chemie (HOH)
Sequence modifications
A: 0 - 0 (PDB: 1OIT)
A: 1 - 298 (UniProt: P24941)
PDBExternal DatabaseDetails
Ser 116Ala 116conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34018.5
Non-Polymers*Number of molecules1
Total formula weight366.4
All*Total formula weight34384.9
*Water molecules are not included.

217705

数据于2024-03-27公开中

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