1NHV

Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE	polymer	578	64261.6	2	UniProt (P26663) Pfam (PF00998) In PDB	Hepatitis C virus subtype 1b	Nonstructural protein NS5B; P66; P70; RNA-directed RNA polymerase
2	A, B	(2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID	non-polymer		550.5	2	Chemie (154)

Sequence modifications

A, B: 1 - 570 (UniProt: P26663)

PDB	External Database	Details
Ala -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128523.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1100.9
All*	Total formula weight	129624.1

*Water molecules are not included.