1NHU
Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | polymer | 578 | 64261.6 | 2 | UniProt (P26663) Pfam (PF00998) In PDB | Hepatitis C virus subtype 1b | Nonstructural protein NS5B; P66; P70; RNA-directed RNA polymerase |
2 | A, B | (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID | non-polymer | 496.3 | 2 | Chemie (153) | |||
3 | water | water | 18.0 | 577 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 570 (UniProt: P26663)
PDB | External Database | Details |
---|---|---|
Ala -7 | - | expression tag |
Ser -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128523.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 992.6 | |
All* | Total formula weight | 129515.8 |