1NF5

Crystal Structure of Lactose Synthase, Complex with Glucose

Replaces:  1J8W

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Alpha-lactalbumin	polymer	123	14015.8	2	UniProt (P29752) Pfam (PF00062) In PDB	Mus musculus (house mouse)	Lactose synthase B protein
2	B, D	beta-1,4-galactosyltransferase	polymer	286	32851.6	2	UniProt (P08037) Pfam (PF13733) Pfam (PF02709) In PDB	Bos taurus (cattle)
3	A, C	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	B, D	beta-D-glucopyranose	non-polymer		180.2	2	Chemie (BGC)
6	C	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7		water	water		18.0	591	Chemie (HOH)

Sequence modifications

B, D: 130 - 402 (UniProt: P08037)

PDB	External Database	Details
Ala 117	-	see remark 999
Ser 118	-	see remark 999
Met 119	-	see remark 999
Thr 120	-	see remark 999
Gly 121	-	see remark 999
Gly 122	-	see remark 999
Gln 123	-	see remark 999
Gln 124	-	see remark 999
Met 125	-	see remark 999
Gly 126	-	see remark 999
Arg 127	-	see remark 999
Gly 128	-	see remark 999
Ser 129	-	see remark 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	93734.9
Non-Polymers*	Number of molecules	7
	Total formula weight	891.0
All*	Total formula weight	94625.9

*Water molecules are not included.