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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

1KC8

Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A23S RRNApolymer2922946034.41GenBank (3377779)Haloarcula marismortui
2B5S RRNApolymer12239318.41GenBank (3377779)Haloarcula marismortui
3CRIBOSOMAL PROTEIN L2polymer23925237.51UniProt (P20276)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L2P, HMAL2, HL4
4DRIBOSOMAL PROTEIN L3polymer33737265.21UniProt (P20279)
Pfam (PF00297)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L3P, HMAL3, HL1
5ERIBOSOMAL PROTEIN L4polymer24626442.11UniProt (P12735)
Pfam (PF00573)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L4E, HMAL4, HL6
6FRIBOSOMAL PROTEIN L5polymer17619420.51UniProt (P14124)
Pfam (PF00673)
Pfam (PF00281)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L5P, HMAL5, HL13
7GRIBOSOMAL PROTEIN L6polymer17719830.51UniProt (P14135)
Pfam (PF00347)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L6P, HMAL6, HL10
8HRIBOSOMAL PROTEIN L7AEpolymer11912600.81UniProt (P12743)
Pfam (PF01248)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN HS6
9IRIBOSOMAL PROTEIN L10polymer34837213.81UniProt (P15825)
Pfam (PF00466)
Pfam (PF17777)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN P0, HMAL10, L10E
10JRIBOSOMAL PROTEIN L10Epolymer16718022.51Pfam (PF00252)
UniProt (by SIFTS) (P60617)
In PDB		Haloarcula marismortui
11KRIBOSOMAL PROTEIN L13polymer14516249.21UniProt (P29198)
Pfam (PF00572)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L13P, HMAL13
12LRIBOSOMAL PROTEIN L14polymer13214216.21UniProt (P22450)
Pfam (PF00238)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L14P, HMAL14, HL27
13MRIBOSOMAL PROTEIN L15polymer16417874.21UniProt (P12737)
Pfam (PF00828)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L15P, HMAL15, HL9
14NRIBOSOMAL PROTEIN L15Epolymer19422856.61Pfam (PF00827)
UniProt (by SIFTS) (P60618)
In PDB		Haloarcula marismortui
15ORIBOSOMAL PROTEIN L18polymer18620509.71UniProt (P14123)
Pfam (PF17144)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L18P, HMAL18, HL12
16PRIBOSOMAL PROTEIN L18Epolymer11512307.71UniProt (P12733)
Pfam (PF00828)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L18E, HL29, L19
17QRIBOSOMAL PROTEIN L19Epolymer14816631.31UniProt (P14119)
Pfam (PF01280)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L19E, HMAL19, HL24
18RRIBOSOMAL PROTEIN L21Epolymer9510436.61UniProt (P12734)
Pfam (PF01157)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L21E, HL31
19SRIBOSOMAL PROTEIN L22polymer15416835.71UniProt (P10970)
Pfam (PF00237)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L22P, HMAL22, HL23
20TRIBOSOMAL PROTEIN L23polymer849481.31UniProt (P12732)
Pfam (PF00276)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L23P, HMAL23, HL25, L21
21URIBOSOMAL PROTEIN L24polymer11913539.81UniProt (P10972)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L24P, HMAL24, HL16, HL15
22VRIBOSOMAL PROTEIN L24Epolymer667233.71UniProt (P14116)
Pfam (PF01246)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L24E, HL21/HL22
23WRIBOSOMAL PROTEIN L29polymer707758.71UniProt (P10971)
Pfam (PF00831)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L29P, HMAL29, HL33
24XRIBOSOMAL PROTEIN L30polymer15417062.91UniProt (P14121)
Pfam (PF00327)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L30P, HMAL30, HL20, HL16
25YRIBOSOMAL PROTEIN L31Epolymer9110253.41UniProt (P18138)
Pfam (PF01198)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L31E, L34, HL30
26ZRIBOSOMAL PROTEIN L32Epolymer24026324.51UniProt (P12736)
Pfam (PF14520)
Pfam (PF01655)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L32E, HL5
271RIBOSOMAL PROTEIN L37Aepolymer738097.81Pfam (PF01780)
UniProt (by SIFTS) (P60619)
In PDB		Haloarcula marismortui
282RIBOSOMAL PROTEIN L37Epolymer566199.01UniProt (P32410)
Pfam (PF01907)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L37E, L35E
293RIBOSOMAL PROTEIN L39Epolymer485844.71UniProt (P22452)
Pfam (PF00832)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEINS L39E, HL39E, HL46E
304RIBOSOMAL PROTEIN L44Epolymer9210815.21UniProt (P32411)
Pfam (PF00935)
In PDB		Haloarcula marismortui50S RIBOSOMAL PROTEIN L44E, LA, HLA
31ABLASTICIDIN Snon-polymer422.42Chemie (BLS)
32A, 4, L, B, C...MAGNESIUM IONnon-polymer24.3117Chemie (MG)
33APOTASSIUM IONnon-polymer39.13Chemie (K)
34A, J, K, M, N...SODIUM IONnon-polymer23.086Chemie (NA)
35K, 4, A, M, N...CHLORIDE IONnon-polymer35.522Chemie (CL)
361, 2, 4, P, VCADMIUM IONnon-polymer112.45Chemie (CD)
37waterwater18.07879Chemie (HOH)
Sequence modifications
A: 2 - 2923 (GenBank: 3377779)
PDBExternal DatabaseDetails
C 560U 3155conflict
D: 1 - 337 (UniProt: P20279)
PDBExternal DatabaseDetails
-Pro 310deletion
Arg 310Phe 311conflict
Q: 1 - 148 (UniProt: P14119)
PDBExternal DatabaseDetails
Lys 71Tyr 71conflict
3: 1 - 48 (UniProt: P22452)
PDBExternal DatabaseDetails
-Arg 31deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains30
Total formula weight1451914.1
Non-Polymers*Number of molecules235
Total formula weight7125.0
All*Total formula weight1459039.2
*Water molecules are not included.

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数据于2024-04-17公开中

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