1J04
Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | alanine--glyoxylate aminotransferase | polymer | 392 | 43391.1 | 1 | UniProt (P21549) Pfam (PF00266) In PDB | Homo sapiens (human) | Serine--pyruvate aminotransferase |
| 2 | A | (AMINOOXY)ACETIC ACID | non-polymer | 91.1 | 1 | Chemie (AOA) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 1 - 392 (UniProt: P21549)
| PDB | External Database | Details |
|---|---|---|
| Arg 170 | Gly 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43391.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 735.7 | |
| All* | Total formula weight | 44126.8 |
