1H07

CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CELL DIVISION PROTEIN KINASE 2	polymer	299	34002.5	1	UniProt (P24941) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	P33 PROTEIN KINASE
2	A	((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2R)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILE	non-polymer		511.4	1	Chemie (MFP)
3	A	((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2S)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILE	non-polymer		511.4	1	Chemie (MFQ)
4		water	water		18.0	200	Chemie (HOH)

Sequence modifications

A: 0 - 0 (PDB: 1H07)
A: 1 - 298 (UniProt: P24941)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34002.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1022.8
All*	Total formula weight	35025.4

*Water molecules are not included.