1DOA

Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PROTEIN (GTP-BINDING PROTEIN)	polymer	191	21254.4	1	UniProt (P60953) Pfam (PF00071) In PDB	Homo sapiens (human)	CDC42
2	B	PROTEIN (GDP-DISSOCIATION INHIBITOR 1)	polymer	219	24633.7	1	UniProt (P19803) Pfam (PF02115) In PDB	Bos taurus (cattle)	RHO GDI 1
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
5	A	GERAN-8-YL GERAN	non-polymer		274.5	1	Chemie (GER)
6		water	water		18.0	50	Chemie (HOH)

Sequence modifications

A: 1 - 188 (UniProt: P60953)

PDB	External Database	Details
Gly -2	-	SEE REMARK 999
Ser -1	-	SEE REMARK 999
His 0	-	SEE REMARK 999
Cmt 188	Cys 188	MODIFIED RESIDUE

B: 1 - 204 (UniProt: P19803)

PDB	External Database	Details
Gly -14	-	SEE REMARK 999
Ser -13	-	SEE REMARK 999
Pro -12	-	SEE REMARK 999
Gly -11	-	SEE REMARK 999
Ile -10	-	SEE REMARK 999
Ser -9	-	SEE REMARK 999
Gly -8	-	SEE REMARK 999
Gly -7	-	SEE REMARK 999
Gly -6	-	SEE REMARK 999
Gly -5	-	SEE REMARK 999
Gly -4	-	SEE REMARK 999
Ile -3	-	SEE REMARK 999
Leu -2	-	SEE REMARK 999
Gly -1	-	SEE REMARK 999
Leu 0	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45888.1
Non-Polymers*	Number of molecules	4
	Total formula weight	766.3
All*	Total formula weight	46654.4

*Water molecules are not included.