1CZ8

VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	V, W	Vascular endothelial growth factor A	polymer	94	10999.7	2	UniProt (P15692) In PDB	Homo sapiens (human)	VEGF-A, Vascular permeability factor, VPF
2	L, X	LIGHT CHAIN OF NEUTRALIZING ANTIBODY	polymer	214	23453.9	2		Mus musculus (house mouse)	Ranibizumab Light Chain
3	H, Y	HEAVY CHAIN OF NEUTRALIZING ANTIBODY	polymer	231	24979.9	2		Mus musculus (house mouse)	Ranibizumab Heavy Chain
4	H, Y	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	419	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	118867.1
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	119059.2

*Water molecules are not included.