Mine: Updated entries

6D37
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TRP-CAGE TR16B R16NVA : ELIMINATION OF PH DEPENDENT INTERACTIONS
Descriptor:ALA-TYR-ALA-GLN-TRP-LEU-ALA-ASP-DAL-GLY-PRO-ALA-SER-DAL-NVA-PRO-PRO-PRO-SER
Authors:Byrne, A., Andersen, N.H.
Deposit date:2018-04-14
Release date:2019-03-13
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Reversing the typical pH stability profile of the Trp-cage.
Biopolymers, 110, 2019
6DY7
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WDR5 IN COMPLEX WITH A WIN SITE INHIBITOR
Descriptor:WD repeat-containing protein 5, N-[3-(2,4-dichlorophenoxy)propyl]-1H-imidazol-2-amine, DIMETHYL SULFOXIDE, ...
Authors:Phan, J., Wang, F., Fesik, S.W.
Deposit date:2018-07-01
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6DYA
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WDR5 IN COMPLEX WITH A WIN SITE INHIBITOR
Descriptor:WD repeat-containing protein 5, N-[(3,5-dichlorophenyl)methyl]-3-[(1H-imidazol-1-yl)methyl]benzamide, SULFATE ION, ...
Authors:Phan, J., Wang, F., Fesik, S.W.
Deposit date:2018-07-01
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E1Y
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DISCOVERY OF POTENT 2-ARYL-6,7-DIHYDRO-5HPYRROLO[ 1,2-A]IMIDAZOLES AS WDR5 WIN-SITE INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN
Descriptor:WD repeat-containing protein 5, N-[(1S)-1-(3-chlorophenyl)ethyl]-3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}benzamide
Authors:Phan, J., Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.219 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E1Z
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DISPLACEMENT OF WDR5 FROM CHROMATIN BY A PHARMACOLOGICAL WIN SITE INHIBITOR WITH PICOMOLAR AFFINITY
Descriptor:WD repeat-containing protein 5, 5-[(1H-imidazol-1-yl)methyl]furan-2-carboxylic acid
Authors:Phan, J., Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E22
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DISPLACEMENT OF WDR5 FROM CHROMATIN BY A PHARMACOLOGICAL WIN SITE INHIBITOR WITH PICOMOLAR AFFINITY
Descriptor:WD repeat-containing protein 5, 3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}-N-[(3,5-dimethoxyphenyl)methyl]-4-fluorobenzamide, SULFATE ION
Authors:Phan, J., Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E23
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DISPLACEMENT OF WDR5 FROM CHROMATIN BY A PHARMACOLOGICAL WIN SITE INHIBITOR WITH PICOMOLAR AFFINITY
Descriptor:WD repeat-containing protein 5, N-[(3,4-dichlorophenyl)methyl]-3-(6-fluoro-2-methylpyridin-3-yl)-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Phan, J., Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E5M
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CRYSTALLOGRAPHIC STRUCTURE OF THE CYCLIC NONAPEPTIDE DERIVED FROM THE BTCI INHIBITOR BOUND TO BETA-TRYPSIN IN SPACE GROUP P 32 2 1
Descriptor:Cationic trypsin, 9MER-PEPTIDE, CALCIUM ION, ...
Authors:Fernandes, J.C., Valadares, N.F., Freitas, S.M., Barbosa, J.A.R.G.
Deposit date:2018-07-20
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:Crystallographic structure of a complex between trypsin and a nonapeptide derived from a Bowman-Birk inhibitor found in Vigna unguiculata seeds.
Arch. Biochem. Biophys., 665, 2019
6EAT
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CRYSTALLOGRAPHIC STRUCTURE OF THE CYCLIC NONAPEPTIDE DERIVED FROM THE BTCI INHIBITOR BOUND TO BETA-TRYPSIN IN SPACE GROUP P 21 21 21.
Descriptor:Cationic trypsin, 9MER-PEPTIDE, CALCIUM ION, ...
Authors:Fernandes, J.C., Valadares, N.F., Freitas, S.M., Barbosa, J.A.R.G.
Deposit date:2018-08-03
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.149 Å)
Cite:Crystallographic structure of a complex between trypsin and a nonapeptide derived from a Bowman-Birk inhibitor found in Vigna unguiculata seeds.
Arch. Biochem. Biophys., 665, 2019
6HY3
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THREE-DIMENSIONAL STRUCTURE OF AGAC FROM ZOBELLIA GALACTANIVORANS
Descriptor:Beta-agarase C, MAGNESIUM ION, GLYCEROL, ...
Authors:Naretto, A., Fanuel, M., Ropartz, D., Rogniaux, H., Larocque, R., Czjzek, M., Tellier, C., Michel, G.
Deposit date:2018-10-19
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The agar-specific hydrolaseZgAgaC from the marine bacteriumZobellia galactanivoransdefines a new GH16 protein subfamily.
J.Biol.Chem., 2019
6I2O
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SOLUTION NMR STRUCTURE OF PILE1 FROM STREPTOCOCCUS SANGUINIS
Descriptor:Type IV pilin PilE1
Authors:Berry, J.L., Xu, Y.
Deposit date:2018-11-01
Release date:2019-03-13
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacteriumStreptococcus sanguinis.
J.Biol.Chem., 2019
6I59
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LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges
To Be Published
6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges
To Be Published
6I86
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CROCAGIN BIOSYNTHETIC GENE J
Descriptor:Uncharacterized protein, GLYCEROL
Authors:Adam, S., Koehnke, J.
Deposit date:2018-11-19
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of CgnJ, a domain of unknown function protein from the crocagin gene cluster.
Acta Crystallogr.,Sect.F, 75, 2019
6I9A
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PORPHYROMONAS GINGIVALIS GINGIPAIN K (KGP) IN COMPLEX WITH INHIBITOR KYT-36
Descriptor:Lys-gingipain W83, UNKNOWN ATOM OR ION, SODIUM ION, ...
Authors:Gomis-Ruth, F.X., Guevara, T., Rofdriguez-Banqueri, A.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavaliable peptidase inhibitor.
Sci Rep, 9, 2019
6I9S
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HROBO2 EXTRACELLULAR DOMAINS 2-3
Descriptor:Roundabout homolog 2, SODIUM ION
Authors:Barak, R., Isupov, N.M., Opatowsky, Y.
Deposit date:2018-11-25
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 2019
6IAA
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HROBO2 ECTODOMAIN
Descriptor:Roundabout homolog 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Barak, R., Isupov, N.M., Opatowsky, Y.
Deposit date:2018-11-26
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 2019
6IMX
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CRYSTAL STRUCTURE OF V30M MUTATED TRANSTHYRETIN IN COMPLEX WITH 18-CROWN-6
Descriptor:Transthyretin, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE
Authors:Yokoyama, T., Kosaka, Y., Matsumoto, K., Kitakami, R., Nabeshima, Y., Mizuguchi, M.
Deposit date:2018-10-24
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crown Ethers as Transthyretin Amyloidogenesis Inhibitors.
J. Med. Chem., 62, 2019
6J4I
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A CONSERVED AND BURIED EDGE-TO-FACE AROMATIC INTERACTION IN SUMO IS VITAL FOR THE SUMO PATHWAY
Descriptor:Small ubiquitin-related modifier 1
Authors:Chatterjee, K.S., Das, R.
Deposit date:2019-01-09
Release date:2019-03-13
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:A conserved and buried edge-to-face aromatic interaction in Small Ubiquitin-like Modifier (SUMO) has a role in SUMO stability and function.
J. Biol. Chem., 2019
6JCJ
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STRUCTURE OF CROLIBULIN IN COMPLEX WITH TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Zhang, Z., Yang, J.
Deposit date:2019-01-29
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
6MW6
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ANTIMICROBIAL LASSO PEPTIDE CITROCIN
Descriptor:Citrocin
Authors:Link, A.J., Cheung-Lee, W.L.
Deposit date:2018-10-29
Release date:2019-03-13
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Discovery and structure of the antimicrobial lasso peptide citrocin.
J. Biol. Chem., 2019
6MZX
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CRYO-EM STRUCTURE OF THE HO BMC SHELL: ICOSAHEDRAL RECONSTRUCTION (MAIN POPULATION)
Descriptor:Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein HO-5815, Microcompartments protein HO-5816
Authors:Greber, B.J., Sutter, M., Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 2019
6NBB
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HORSE LIVER ALCOHOL DEHYDROGENASE DETERMINED USING SINGLE-PARTICLE CRYO-EM AT 200 KEV
Descriptor:Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2018-12-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.
Nat Commun, 10, 2019
6NBC
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HUMAN METHEMOGLOBIN STATE 1 DETERMINED USING SINGLE-PARTICLE CRYO-EM AT 200 KEV
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2018-12-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.
Nat Commun, 10, 2019
6NMF
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SFX STRUCTURE OF REDUCED CYTOCHROME C OXIDASE AT ROOM TEMPERATURE
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Rousseau, D.L., Yeh, S.-R., Ishigami, I.
Deposit date:2019-01-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Snapshot of an oxygen intermediate in the catalytic reaction of cytochromecoxidase.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019