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6MTV
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BU of 6mtv by Molmil
Crystal structure of human Scribble PDZ1:MCC complex
Descriptor: Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ...
Authors:Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M.
Deposit date:2018-10-22
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
6MTU
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BU of 6mtu by Molmil
Crystal structure of human Scribble PDZ1:pMCC complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ...
Authors:Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M.
Deposit date:2018-10-22
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
5K99
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BU of 5k99 by Molmil
Crystal structure of microcin immunity protein MccF from Bacillus anthracis in complex with McC
Descriptor: Microcin C, Microcin C7 self-immunity protein mccF
Authors:Nocek, B, Kulikovsky, A, Severinov, K, Dubiley, S, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-05-31
Release date:2017-03-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of microcin immunity protein MccF from Bacillus anthracis in complex with McC
To Be Published
5LCW
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BU of 5lcw by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
Deposit date:2016-06-22
Release date:2016-08-10
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular basis of APC/C regulation by the spindle assembly checkpoint.
Nature, 536, 2016
3U9T
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BU of 3u9t by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme
Descriptor: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
3U9S
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BU of 3u9s by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Methylcrotonyl-CoA carboxylase, ...
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
3U9R
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BU of 3u9r by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC), beta subunit
Descriptor: Methylcrotonyl-CoA carboxylase, beta-subunit, PENTAETHYLENE GLYCOL, ...
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
6TLJ
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BU of 6tlj by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Barford, D.
Deposit date:2019-12-02
Release date:2020-02-19
Last modified:2020-06-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
5KHU
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BU of 5khu by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B.
Deposit date:2016-06-15
Release date:2016-09-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
3QIB
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BU of 3qib by Molmil
Crystal structure of the 2B4 TCR in complex with MCC/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 beta chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-26
Release date:2011-04-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3QIU
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BU of 3qiu by Molmil
Crystal structure of the 226 TCR in complex with MCC/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ...
Authors:Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3QIW
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BU of 3qiw by Molmil
Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ...
Authors:Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3GJZ
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BU of 3gjz by Molmil
Crystal structure of microcin immunity protein MccF from Bacillus anthracis str. Ames
Descriptor: Microcin immunity protein MccF
Authors:Nocek, B, Zhou, M, Kwon, K, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-03-09
Release date:2009-04-14
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
6F0X
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BU of 6f0x by Molmil
Cryo-EM structure of TRIP13 in complex with ATP gamma S, p31comet, C-Mad2 and Cdc20
Descriptor: Cell division cycle protein 20 homolog, MAD2L1-binding protein, Mitotic spindle assembly checkpoint protein MAD2A, ...
Authors:Alfieri, C, Chang, L, Barford, D.
Deposit date:2017-11-20
Release date:2018-05-02
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13.
Nature, 559, 2018
7B1H
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BU of 7b1h by Molmil
Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1F
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BU of 7b1f by Molmil
Orthorhombic P212121 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1J
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BU of 7b1j by Molmil
Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-25
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
3T5M
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BU of 3t5m by Molmil
Crystal structure of the S112A mutant of mycrocine immunity protein (MccF) with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCEROL, Microcin immunity protein MccF
Authors:Nocek, B, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-27
Release date:2011-09-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
3SR3
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BU of 3sr3 by Molmil
Crystal structure of the w180a mutant of microcin immunity protein mccf from Bacillus anthracis shows the active site loop in the open conformation.
Descriptor: Microcin immunity protein MccF
Authors:Nocek, B, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-06
Release date:2011-08-10
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (1.495 Å)
Cite:Structural and functional characterization of microcin C resistance peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
3U1B
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BU of 3u1b by Molmil
Crystal structure of the S238R mutant of mycrocine immunity protein (MccF) with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF
Authors:Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-09-29
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
3TYX
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BU of 3tyx by Molmil
Crystal structure of the F177S mutant of mycrocine immunity protein (MccF) with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF
Authors:Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-09-26
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
J.Mol.Biol., 420, 2012
4AEZ
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BU of 4aez by Molmil
Crystal Structure of Mitotic Checkpoint Complex
Descriptor: MITOTIC SPINDLE CHECKPOINT COMPONENT MAD2, MITOTIC SPINDLE CHECKPOINT COMPONENT MAD3, WD REPEAT-CONTAINING PROTEIN SLP1
Authors:Kulkarni, K.A, Chao, W.C.H, Zhang, Z, Barford, D.
Deposit date:2012-01-13
Release date:2012-03-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Mitotic Checkpoint Complex
Nature, 484, 2012
5WC2
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BU of 5wc2 by Molmil
Crystal Structure of ADP-bound human TRIP13
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Pachytene checkpoint protein 2 homolog
Authors:Jeong, B.-C, Luo, X.
Deposit date:2017-06-29
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.
Nat Commun, 8, 2017
5KHR
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BU of 5khr by Molmil
Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A.
Deposit date:2016-06-15
Release date:2016-08-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
3R96
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BU of 3r96 by Molmil
Crystal structure of Microcin C7 self immunity acetyltransferase MccE in complex with Acetyl-CoA and AMP
Descriptor: ACETYL COENZYME *A, ADENOSINE MONOPHOSPHATE, MccE protein
Authors:Nair, S.K, Agarwal, V.
Deposit date:2011-03-24
Release date:2011-04-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Basis for Microcin C7 Inactivation by the MccE Acetyltransferase.
J.Biol.Chem., 286, 2011

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