4XJL
  • Download 4xjl
  • View 4xjl
Molmil generated image of 4xjl
CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE (BIOA) FROM MYCOBACTERIUM TUBERCULOSIS, COMPLEXED WITH A HTS LEAD COMPOUND
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, TRIETHYLENE GLYCOL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Finzel, B.C., Dai, R.
Deposit date:2015-01-08
Release date:2016-01-20
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Fragment based inhibitor design of Mycobacterium tuberculosis BioA (http://hdl.handle.net/11299/171084)
Thesis, University Of Minnesota, 2015
4XJM
  • Download 4xjm
  • View 4xjm
Molmil generated image of 4xjm
CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE (BIOA) FROM MYCOBACTERIUM TUBERCULOSIS, COMPLEXED WITH A HTS LEAD COMPOUND
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, 3-{1-[(5-acetylthiophen-2-yl)carbonyl]piperidin-4-yl}-N-(3-methoxyphenyl)propanamide, PYRIDOXAL-5'-PHOSPHATE
Authors:Finzel, B.C., Dai, R.
Deposit date:2015-01-08
Release date:2016-01-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Fragment based inhibitor design of Mycobacterium tuberculosis BioA (http://hdl.handle.net/11299/171084)
Thesis, University of Minnesota, 2015
4XJO
  • Download 4xjo
  • View 4xjo
Molmil generated image of 4xjo
CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE (BIOA) FROM MYCOBACTERIUM TUBERCULOSIS, COMPLEXED WITH AN INHIBITOR OPTIMIZED FROM HTS LEAD
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, 5-[4-(3-chlorobenzoyl)piperazin-1-yl]-1H-inden-1-one, ...
Authors:Finzel, B.C., Dai, R.
Deposit date:2015-01-08
Release date:2016-01-20
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
J. Med. Chem., 60, 2017
4XJP
  • Download 4xjp
  • View 4xjp
Molmil generated image of 4xjp
CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE (BIOA) FROM MYCOBACTERIUM TUBERCULOSIS, COMPLEXED WITH AN INHIBITOR OPTIMIZED FROM HTS LEAD
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, 1-{4-[4-(1,3-benzodioxol-5-ylcarbonyl)piperazin-1-yl]phenyl}ethanone, ...
Authors:Finzel, B.C., Dai, R.
Deposit date:2015-01-08
Release date:2016-01-20
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
J. Med. Chem., 60, 2017
2I8E
  • Download 2i8e
  • View 2i8e
Molmil generated image of 2i8e
STRUCTURE OF SSO1404, A PREDICTED DNA REPAIR-ASSOCIATED PROTEIN FROM SULFOLOBUS SOLFATARICUS P2
Descriptor:Hypothetical protein, IODIDE ION
Authors:Wang, S., Zimmerman, M.D., Kudritska, M., Chruszcz, M., Savchenko, A., Edwards, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-01
Release date:2006-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
J.Biol.Chem., 283, 2008
2MBM
  • Download 2mbm
  • View 2mbm
Molmil generated image of 2mbm
SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED TOP7 FOLD PROTEIN TOP7M13, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR33
Descriptor:Top7 Fold Protein Top7m13
Authors:Liu, G., Zanghellini, A.L., Chan, K., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-08-02
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33
To be Published
2IAI
  • Download 2iai
  • View 2iai
Molmil generated image of 2iai
CRYSTAL STRUCTURE OF SCO3833, A MEMBER OF THE TETR TRANSCRIPTIONAL REGULATOR FAMILY FROM STREPTOMYCES COELICOLOR A3
Descriptor:Putative transcriptional regulator SCO3833
Authors:Zimmerman, M.D., Xu, X., Wang, S., Gu, J., Chruszcz, M., Cymborowski, M., Savchenko, A., Edwards, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-08
Release date:2006-09-26
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of SCO3833, a member of the TetR transcriptional regulator family from Streptomyces coelicolor A3
To be Published
2MBL
  • Download 2mbl
  • View 2mbl
Molmil generated image of 2mbl
SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED TOP7 FOLD PROTEIN TOP7M13, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR33
Descriptor:Top7 Fold Protein Top7m13
Authors:Liu, G., Zanghellini, A.L., Chan, K., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-08-02
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33
To be Published
3B5U
  • Download 3b5u
  • View 3b5u
Molmil generated image of 3b5u
ACTIN FILAMENT MODEL FROM EXTENDED FORM OF ACROMSOMAL BUNDLE IN THE LIMULUS SPERM
Descriptor:Actin, alpha skeletal muscle
Authors:Cong, Y., Topf, M., Sali, A., Matsudaira, P., Dougherty, M., Chiu, W., Schmid, M.F.
Deposit date:2007-10-26
Release date:2008-04-15
Last modified:2018-07-18
Method:ELECTRON CRYSTALLOGRAPHY (9.5 Å)
Cite:Crystallographic conformers of actin in a biologically active bundle of filaments
J.Mol.Biol., 375, 2008
3B63
  • Download 3b63
  • View 3b63
Molmil generated image of 3b63
ACTIN FILAMENT MODEL IN THE EXTENDED FORM OF ACROMSOMAL BUNDLE IN THE LIMULUS SPERM
Descriptor:Actin
Authors:Cong, Y., Topf, M., Sali, A., Matsudaira, P., Dougherty, M., Chiu, W., Schmid, M.F.
Deposit date:2007-10-26
Release date:2008-11-18
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Crystallographic conformers of actin in a biologically active bundle of filaments.
J.Mol.Biol., 375, 2008
3Q6C
  • Download 3q6c
  • View 3q6c
Molmil generated image of 3q6c
X-RAY CRYSTAL STRUCTURE OF DUF2500 (PF10694) FROM KLEBSIELLA PNEUMONIAE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET KPR96
Descriptor:probable receptor YhhM
Authors:Seetharaman, J., Su, M., Wang, D., Ciccosanti, C., Sahdev, S., Nair, R., Rost, B., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-12-31
Release date:2011-08-10
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structure of duf2500 (pf10694) from klebsiella pneumoniae, northeast structural genomics consortium target kpr96
To be Published
4YTA
  • Download 4yta
  • View 4yta
Molmil generated image of 4yta
BOND LENGTH ANALYSIS OF ASP, GLU AND HIS RESIDUES IN TRYPSIN AT 1.2A RESOLUTION
Descriptor:Cationic trypsin, GLYCEROL, SULFATE ION, ...
Authors:Fisher, S.J., Helliwell, J.R., Blakeley, M.P., Cianci, M., McSweeny, S.
Deposit date:2015-03-17
Release date:2015-05-27
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness.
Acta Crystallogr. D Biol. Crystallogr., 68, 2012
5HMJ
  • Download 5hmj
  • View 5hmj
Molmil generated image of 5hmj
RE-REFINEMENT OF 4XAN: HEN LYSOZYME WITH CARBOPLATIN IN SODIUM BROMIDE SOLUTION
Descriptor:Lysozyme C, BROMIDE ION, SODIUM ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-01-16
Release date:2016-03-02
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.299901 Å)
Cite:Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5JFD
  • Download 5jfd
  • View 5jfd
Molmil generated image of 5jfd
THROMBIN IN COMPLEX WITH (S)-N-(2-(AMINOMETHYL)-5-CHLOROBENZYL)-1-((BENZYLSULFONYL)-D-ARGINYL)PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Prothrombin, Hirudin variant-2, (2S)-N-[[2-(aminomethyl)-5-chloro-phenyl]methyl]-1-[(2R)-5-carbamimidamido-2-(phenylmethylsulfonylamino)pentanoyl]pyrrolidine-2-carboxamide, ...
Authors:Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-04-19
Release date:2017-05-24
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Thrombin in complex with (S)-N-(2-(aminomethyl)-5-chlorobenzyl)-1-((benzylsulfonyl)-D-arginyl)pyrrolidine-2-carboxamide
to be published
5JLT
  • Download 5jlt
  • View 5jlt
Molmil generated image of 5jlt
THE CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 MOTA C-TERMINAL DOMAIN IN COMPLEX WITH DSDNA REVEALS A NOVEL PROTEIN-DNA RECOGNITION MOTIF
Descriptor:Middle transcription regulatory protein motA, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*TP*GP*CP*TP*TP*AP*AP*TP*AP*AP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*GP*AP*TP*TP*AP*TP*TP*AP*AP*GP*CP*AP*AP*AP*GP*CP*TP*TP*C)-3')
Authors:Cuypers, M.G., Robertson, R.M., Knipling, L., Hinton, D.M., White, S.W.
Deposit date:2016-04-27
Release date:2017-05-03
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:The crystal structure of the bacteriophage T4 MotA C-terminal domain in complex with dsDNA reveals a novel protein-DNA recognition motif
To Be Published
5JZY
  • Download 5jzy
  • View 5jzy
Molmil generated image of 5jzy
THROMBIN IN COMPLEX WITH (S)-1-((R)-2-AMINO-3-CYCLOHEXYLPROPANOYL)-N-(4-CARBAMIMIDOYLBENZYL)PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Prothrombin, Hirudin variant-2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-05-17
Release date:2017-06-07
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Thrombin in complex with (S)-N-(2-(aminomethyl)-5-chlorobenzyl)-1-((benzylsulfonyl)-D-arginyl)pyrrolidine-2-carboxamide
to be published
5LCE
  • Download 5lce
  • View 5lce
Molmil generated image of 5lce
THROMBIN IN COMPLEX WITH (S)-1-((R)-2-AMINO-3-CYCLOHEXYLPROPANOYL)-N-(5-CHLORO-2-(HYDROXYMETHYL)BENZY L)PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Prothrombin, Hirudin variant-2, (2~{S})-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]-~{N}-[[5-chloranyl-2-(hydroxymethyl)phenyl]methyl]pyrrolidine-2-carboxamide, ...
Authors:Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-06-21
Release date:2017-07-26
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(5-chloro-2-(hydroxymethyl)benzy l)pyrrolidine-2-carboxamide
to be published
5LFZ
  • Download 5lfz
  • View 5lfz
Molmil generated image of 5lfz
T48 DEACETYLASE
Descriptor:ArCE4A, NICKEL (II) ION
Authors:Rothweiler, U.
Deposit date:2016-07-05
Release date:2017-08-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.561 Å)
Cite:Structure and function of a CE4 deacetylase isolated from a marine environment.
PLoS ONE, 12, 2017
5LGC
  • Download 5lgc
  • View 5lgc
Molmil generated image of 5lgc
T48 DEACETYLASE WITH SUBSTRATE
Descriptor:ArCE4A, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Rothweiler, U.
Deposit date:2016-07-06
Release date:2017-08-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure and function of a CE4 deacetylase isolated from a marine environment.
PLoS ONE, 12, 2017
5M9Y
  • Download 5m9y
  • View 5m9y
Molmil generated image of 5m9y
NMR SOLUTION STRUCTURE OF HARZIANIN HK-VI IN DPC MICELLES
Descriptor:Harzianin HK-VI
Authors:Kara, S., Zamora-Carreras, H., Afonin, S., Grage, S.L., Ulrich, A.S., Jimenez, M.A.
Deposit date:2016-11-02
Release date:2018-02-28
Method:SOLUTION NMR
Cite:11-mer peptaibol Harzianin VI: conformational and biological analysis
To Be Published
5MAS
  • Download 5mas
  • View 5mas
Molmil generated image of 5mas
PEPTAIBOL BERGOFUNGIN A
Descriptor:Bergofungin A
Authors:Gessmann, R., Petratos, K.
Deposit date:2016-11-04
Release date:2017-02-22
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (0.84 Å)
Cite:A natural, single-residue substitution yields a less active peptaibiotic: the structure of bergofungin A at atomic resolution.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5MJT
  • Download 5mjt
  • View 5mjt
Molmil generated image of 5mjt
THROMBIN MUTANT A190S IN COMPLEX WITH (S) -1 - ((R) -2-AMINO-3,3-DIPHENYLPROPANOYL) -N- (3-CHLOROBENZYL) PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ...
Authors:Marca, A., Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-12-01
Release date:2017-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide
to be published
5MLS
  • Download 5mls
  • View 5mls
Molmil generated image of 5mls
THROMBIN MUTANT A190S IN COMPLEX WITH (S)-1-(D-PHENYLALANYL)-N-(3-CHLOROBENZYL)PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ...
Authors:Marca, A., Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Thrombin Mutante A190S in complex with (S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide
to be published
5MM6
  • Download 5mm6
  • View 5mm6
Molmil generated image of 5mm6
THROMBIN MUTANT A190S IN COMPLEX WITH (S)-1-(D-PHENYLALANYL)-N-(4-CARBAMIMIDOYLBENZYL)PYRROLIDINE-2-CARBOXAMIDE
Descriptor:Thrombin light chain, thrombin heavy chain, Hirudin variant-2, ...
Authors:Marca, A., Sandner, A., Heine, A., Klebe, G.
Deposit date:2016-12-08
Release date:2017-12-20
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Thrombin Mutant A190S in complex with (S)-1-(D-phenylalanyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide
to be published
6FYX
  • Download 6fyx
  • View 6fyx
Molmil generated image of 6fyx
STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C1)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan