3EEB
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STRUCTURE OF THE V. CHOLERAE RTX CYSTEINE PROTEASE DOMAIN
Descriptor:RTX toxin RtxA, INOSITOL HEXAKISPHOSPHATE, SODIUM ION
Authors:Lupardus, P.J., Shen, A., Bogyo, M., Garcia, K.C.
Deposit date:2008-09-04
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain
Science, 322, 2008
3FZY
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CRYSTAL STRUCTURE OF PRE-CLEAVAGE FORM OF CYSTEINE PROTEASE DOMAIN FROM VIBRIO CHOLERAE RTXA TOXIN
Descriptor:RTX toxin RtxA, INOSITOL HEXAKISPHOSPHATE, CHLORIDE ION, ...
Authors:Shuvalova, L., Minasov, G., Prochazkova, K., Satchell, K.J.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-01-26
Release date:2009-02-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and molecular mechanism for autoprocessing of MARTX toxin of Vibrio cholerae at multiple sites
J.Biol.Chem., 284, 2009
3GCD
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STRUCTURE OF THE V. CHOLERAE RTX CYSTEINE PROTEASE DOMAIN IN COMPLEX WITH AN AZA-LEUCINE PEPTIDE INHIBITOR
Descriptor:RTX toxin RtxA, ethyl (5S,8S,14S)-14-hydroxy-5,8,11-tris(2-methylpropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,11-tetraazapentadecan-15-oate, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Lupardus, P.J., Garcia, K.C., Shen, A., Bogyo, M.
Deposit date:2009-02-21
Release date:2009-05-26
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin.
Nat.Chem.Biol., 5, 2009
3HO6
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STRUCTURE-FUNCTION ANALYSIS OF INOSITOL HEXAKISPHOSPHATE-INDUCED AUTOPROCESSING IN CLOSTRIDIUM DIFFICILE TOXIN A
Descriptor:Toxin A, INOSITOL HEXAKISPHOSPHATE
Authors:Pruitt, R.N., Lacy, D.B.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A.
J.Biol.Chem., 284, 2009
3PA8
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STRUCTURE OF THE C. DIFFICILE TCDB CYSTEINE PROTEASE DOMAIN IN COMPLEX WITH A PEPTIDE INHIBITOR
Descriptor:Toxin B, N-acetylglycyl-N-[(3S)-1-hydroxy-5-methyl-2-oxohexan-3-yl]-L-serinamide, CALCIUM ION, ...
Authors:Lupardus, P.J., Garcia, K.C.
Deposit date:2010-10-18
Release date:2010-12-15
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB.
Chem.Biol., 17, 2010
3PEE
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STRUCTURE OF THE C. DIFFICILE TCDB CYSTEINE PROTEASE DOMAIN
Descriptor:Toxin B, CALCIUM ION, INOSITOL HEXAKISPHOSPHATE
Authors:Lupardus, P.J., Garcia, K.C.
Deposit date:2010-10-26
Release date:2011-02-16
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins.
Nat.Struct.Mol.Biol., 18, 2011
6EN3
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CRYSTAL STRUCTURE OF FULL LENGTH ENDOS FROM STREPTOCOCCUS PYOGENES IN COMPLEX WITH G2 OLIGOSACCHARIDE.
Descriptor:Endo-beta-N-acetylglucosaminidase F2,Multifunctional-autoprocessing repeats-in-toxin, CALCIUM ION, NICKEL (II) ION, ...
Authors:Trastoy, B., Klontz, E.H., Orwenyo, J., Marina, A., Wang, L.X., Sundberg, E.J., Guerin, M.E.
Deposit date:2017-10-04
Release date:2018-06-13
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.
Nat Commun, 9, 2018
4R04
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CLOSTRIDIUM DIFFICILE TOXIN A (TCDA)
Descriptor:Toxin A, ZINC ION
Authors:Lacy, D.B., Spiller, B.W., Rutherford, S.A.
Deposit date:2014-07-29
Release date:2016-01-06
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Glucosyl Transferase Structure
Nat Microbiol, 2016
6AR6
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CLOSTRIDIOIDES DIFFICILE TOXINB WITH DLD-4 DARPIN
Descriptor:Toxin B, DLD-4 darpin
Authors:Zhang, J., Jiang, M.
Deposit date:2017-08-21
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Clostridioides difficile toxinB with DLD-4 darpin
To Be Published
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