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4XQ7
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BU of 4xq7 by Molmil
The crystal structure of the OAS-like domain (OLD) of human OASL
Descriptor: 2'-5'-oligoadenylate synthase-like protein
Authors:Ibsen, M.S, Gad, H.H, Andersen, L.L, Hornung, V, Julkunen, I, Sarkar, S.N, Hartmann, R.
Deposit date:2015-01-19
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Nucleic Acids Res., 43, 2015
4S3N
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BU of 4s3n by Molmil
Crystal structure of human OAS3 domain I in complex with dsRNA
Descriptor: 2'-5'-oligoadenylate synthase 3, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Donovan, J, Whitney, G, Rath, S, Korennykh, A.
Deposit date:2015-02-26
Release date:2015-03-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.
Proc.Natl.Acad.Sci.USA, 112, 2015
1PX5
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BU of 1px5 by Molmil
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Descriptor: 2'-5'-oligoadenylate synthetase 1, SULFATE ION
Authors:Hartmann, R, Justesen, J, Sarkar, S.N, Sen, G.C, Yee, V.C.
Deposit date:2003-07-02
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Mol.Cell, 12, 2003
4IG8
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BU of 4ig8 by Molmil
Structural basis for cytosolic double-stranded RNA surveillance by human OAS1
Descriptor: 2'-5'-oligoadenylate synthase 1, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Donovan, J, Korennykh, A.
Deposit date:2012-12-16
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4RWP
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BU of 4rwp by Molmil
Crystal structure of porcine OAS1 in complex with dsRNA
Descriptor: 2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWQ
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BU of 4rwq by Molmil
Crystal structure of the apo-state of porcine OAS1
Descriptor: 2'-5'-oligoadenylate synthase 1
Authors:Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWN
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BU of 4rwn by Molmil
Crystal structure of the pre-reactive state of porcine OAS1
Descriptor: 2'-5'-oligoadenylate synthase 1, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
Authors:Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWO
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BU of 4rwo by Molmil
Crystal structure of the porcine OAS1 L149R mutant in complex with dsRNA and ApCpp in the AMP donor position
Descriptor: 2'-5'-oligoadenylate synthase 1, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
Authors:Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015

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