4S3N
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CRYSTAL STRUCTURE OF HUMAN OAS3 DOMAIN I IN COMPLEX WITH DSRNA
Descriptor:2'-5'-oligoadenylate synthase 3, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Donovan, J., Whitney, G., Rath, S., Korennykh, A.
Deposit date:2015-02-26
Release date:2015-03-25
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.
Proc.Natl.Acad.Sci.USA, 112, 2015
1PX5
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CRYSTAL STRUCTURE OF THE 2'-SPECIFIC AND DOUBLE-STRANDED RNA-ACTIVATED INTERFERON-INDUCED ANTIVIRAL PROTEIN 2'-5'-OLIGOADENYLATE SYNTHETASE
Descriptor:2'-5'-oligoadenylate synthetase 1, SULFATE ION
Authors:Hartmann, R., Justesen, J., Sarkar, S.N., Sen, G.C., Yee, V.C.
Deposit date:2003-07-02
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Mol.Cell, 12, 2003
4RWN
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CRYSTAL STRUCTURE OF THE PRE-REACTIVE STATE OF PORCINE OAS1
Descriptor:2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3'), ...
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWO
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CRYSTAL STRUCTURE OF THE PORCINE OAS1 L149R MUTANT IN COMPLEX WITH DSRNA AND APCPP IN THE AMP DONOR POSITION
Descriptor:RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3'), 2'-5'-oligoadenylate synthase 1, ...
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWP
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CRYSTAL STRUCTURE OF PORCINE OAS1 IN COMPLEX WITH DSRNA
Descriptor:2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWQ
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CRYSTAL STRUCTURE OF THE APO-STATE OF PORCINE OAS1
Descriptor:2'-5'-oligoadenylate synthase 1
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
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