1BGX
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TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB
Descriptor:TAQ DNA POLYMERASE, TP7 MAB
Authors:Murali, R., Sharkey, D.J., Daiss, J.L., Krishna Murthy, H.M.
Deposit date:1998-06-02
Release date:1998-10-14
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
1JXE
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STOFFEL FRAGMENT OF TAQ DNA POLYMERASE I
Descriptor:TAQ DNA POLYMERASE I
Authors:Oefner, C., Gelfand, D.H., Stoffel, S., Winkler, F.K.
Deposit date:1996-10-09
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:

1KTQ
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DNA POLYMERASE
Descriptor:DNA POLYMERASE I
Authors:Korolev, S., Waksman, G.
Deposit date:1995-08-16
Release date:1996-11-08
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
Proc.Natl.Acad.Sci.USA, 92, 1995
1QSS
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DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor:5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', DNA POLYMERASE I, ...
Authors:Li, Y., Mitaxov, V., Waksman, G.
Deposit date:1999-06-23
Release date:1999-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QSY
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DDATP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor:5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', DNA POLYMERASE I, ...
Authors:Li, Y., Mitaxov, V., Waksman, G.
Deposit date:1999-06-24
Release date:1999-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QTM
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DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor:5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3', 5'-D(*AP*AP*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', DNA POLYMERASE I, ...
Authors:Li, Y., Mitaxov, V., Waksman, G.
Deposit date:1999-06-28
Release date:1999-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1TAQ
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STRUCTURE OF TAQ DNA POLYMERASE
Descriptor:TAQ DNA POLYMERASE, B-2-OCTYLGLUCOSIDE, ZINC ION
Authors:Kim, Y., Eom, S.H., Wang, J., Lee, D.-S., Suh, S.W., Steitz, T.A.
Deposit date:1996-06-04
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Thermus aquaticus DNA polymerase.
Nature, 376, 1995
1TAU
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TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX
Descriptor:DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), PROTEIN (TAQ POLYMERASE), ...
Authors:Eom, S.H., Wang, J., Steitz, T.A.
Deposit date:1996-06-17
Release date:1997-04-18
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Taq ploymerase with DNA at the polymerase active site.
Nature, 382, 1996
3KTQ
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CRYSTAL STRUCTURE OF AN ACTIVE TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor:DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'), DNA (5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), PROTEIN (LARGE FRAGMENT OF DNA POLYMERASE I), ...
Authors:Li, Y., Waksman, G.
Deposit date:1998-07-28
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.
EMBO J., 17, 1998
3LWL
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STRUCTURE OF KLENOW FRAGMENT OF TAQ POLYMERASE IN COMPLEX WITH AN ABASIC SITE
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-02-24
Release date:2010-05-05
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Replication through an abasic DNA lesion: structural basis for adenine selectivity
Embo J., 29, 2010
3LWM
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STRUCTURE OF THE LARGE FRAGMENT OF THERMUS AQUATICUS DNA POLYMERASE I IN COMPLEX WITH A BLUNT-ENDED DNA AND DDATP
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-02-24
Release date:2010-05-05
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:Replication through an abasic DNA lesion: structural basis for adenine selectivity
Embo J., 29, 2010
3M8R
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CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH TRAPPED 4'-ETHYLATED DTTP
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Diederichs, K., Marx, A., Betz, K.
Deposit date:2010-03-19
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA polymerases caught processing size-augmented nucleotide probes.
Angew.Chem.Int.Ed.Engl., 49, 2010
3M8S
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CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH TRAPPED 4'-METHYLATED DTTP
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Diederichs, K., Marx, A., Betz, K.
Deposit date:2010-03-19
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA polymerases caught processing size-augmented nucleotide probes.
Angew.Chem.Int.Ed.Engl., 49, 2010
3OJS
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SNAPSHOTS OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS PROCESSING C5 MODIFIED THYMIDINES
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-08-23
Release date:2010-12-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OJU
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SNAPSHOT OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS PROCESSING C5 MODIFIED THYMIDIES
Descriptor:DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-08-23
Release date:2010-12-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PO4
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STRUCTURE OF A MUTANT OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN COMPLEX WITH A BLUNT-ENDED DNA AND DDATP
Descriptor:DNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), DNA (5'-D(*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-11-22
Release date:2011-06-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.
Chembiochem, 12, 2011
3PO5
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STRUCTURE OF A MUTANT OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AUQATICUS IN COMPLEX WITH AN ABASIC SITE AND DDATP
Descriptor:DNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), DNA (5'-D(P*(3DR)P*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2010-11-22
Release date:2011-06-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.
Chembiochem, 12, 2011
3PY8
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CRYSTAL STRUCTURE OF A MUTANT OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH DNA AND DDCTP
Descriptor:DNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Schnur, A., Marx, A., Welte, W., Diederichs, K.
Deposit date:2010-12-12
Release date:2011-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.
Chembiochem, 12, 2011
3RR7
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BINARY STRUCTURE OF THE LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO AN ABASIC SITE
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2011-04-29
Release date:2012-02-15
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
3RR8
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TERNARY STRUCTURE OF THE LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO AN ABASIC SITE AND A DDGTP
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2011-04-29
Release date:2012-02-15
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
3RRG
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TERNARY STRUCTURE OF THE LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO AN ABASIC SITE AND A DDGTP
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2011-04-29
Release date:2012-02-15
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
3RRH
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TERNARY STRUCTURE OF THE LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO AN ABASIC SITE AND A DDTTP
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3'), ...
Authors:Marx, A., Diederichs, K., Obeid, S.
Deposit date:2011-04-29
Release date:2012-02-15
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
J.Biol.Chem., 287, 2012
3RTV
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CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH NATURAL PRIMER/TEMPLATE DNA
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), ...
Authors:Marx, A., Diederichs, K., Betz, K.
Deposit date:2011-05-04
Release date:2012-05-30
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
3SV3
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CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH THE ARTIFICIAL BASE PAIR DNAM-D5SICSTP
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Betz, K., Diederichs, K., Marx, A.
Deposit date:2011-07-12
Release date:2012-06-06
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
3SV4
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CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN AN OPEN BINARY COMPLEX WITH DT AS TEMPLATING NUCLEOBASE
Descriptor:DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Betz, K., Diederichs, K., Marx, A.
Deposit date:2011-07-12
Release date:2012-06-06
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
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