Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6WGL
DownloadVisualize
BU of 6wgl by Molmil
Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dupilumab Fab heavy chain, ...
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6OEL
DownloadVisualize
BU of 6oel by Molmil
Engineered Fab bound to IL-4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, Interleukin-4 receptor subunit alpha, ...
Authors:Jude, K.M, Moraga, I, Spangler, J.B, Garcia, K.C.
Deposit date:2019-03-27
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A strategy for the selection of monovalent antibodies that span protein dimer interfaces.
J.Biol.Chem., 294, 2019
5E4E
DownloadVisualize
BU of 5e4e by Molmil
Engineered Interleukin-13 bound to receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ...
Authors:Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C.
Deposit date:2015-10-05
Release date:2015-12-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
3BPL
DownloadVisualize
BU of 3bpl by Molmil
Crystal structure of the IL4-IL4R-Common Gamma ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPO
DownloadVisualize
BU of 3bpo by Molmil
Crystal structure of the IL13-IL4R-IL13Ra ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPN
DownloadVisualize
BU of 3bpn by Molmil
Crystal structure of the IL4-IL4R-IL13Ra ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13 receptor alpha-1 chain, Interleukin-4, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
1IAR
DownloadVisualize
BU of 1iar by Molmil
INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX
Descriptor: PROTEIN (INTERLEUKIN-4 RECEPTOR ALPHA CHAIN), PROTEIN (INTERLEUKIN-4)
Authors:Hage, T, Sebald, W, Reinemer, P.
Deposit date:1999-02-25
Release date:2000-03-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface.
Cell(Cambridge,Mass.), 97, 1999

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon