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1KS6
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Transforming Growth Factor Beta type II receptor ligand binding domain
Descriptor: TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR
Authors:Marlow, M.S, Brown, C.B, Barnett, J.V, Krezel, A.M.
Deposit date:2002-01-10
Release date:2003-02-25
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the chick TGFb type II receptor ligand binding domain
J.Mol.Biol., 326, 2003
1KTZ
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Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3
Descriptor: TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3
Authors:Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P.
Deposit date:2002-01-18
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.
Nat.Struct.Biol., 9, 2002
1M9Z
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CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Descriptor: GLYCEROL, TGF-BETA RECEPTOR TYPE II
Authors:Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D.
Deposit date:2002-07-30
Release date:2002-09-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Structure, 10, 2002
1PLO
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TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN
Descriptor: TGF-beta receptor type II
Authors:Deep, S, Walker III, K.P, Shu, Z, Hinck, A.P.
Deposit date:2003-06-08
Release date:2003-09-23
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the TGF-beta type II receptor extracellular domain
Biochemistry, 42, 2003
2PJY
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BU of 2pjy by Molmil
Structural basis for cooperative assembly of the TGF-beta signaling complex
Descriptor: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-3
Authors:Groppe, J, Zubieta, C.
Deposit date:2007-04-16
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.
Mol.Cell, 29, 2008
3KFD
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Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily
Descriptor: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-1
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-27
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.995 Å)
Cite:Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily.
J.Biol.Chem., 285, 2010
4P7U
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Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, TGF-beta receptor type-2
Authors:Wangkanont, K, Forest, K.T.
Deposit date:2014-03-27
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain.
Protein Expr.Purif., 115, 2015
4XJJ
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Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201
Descriptor: 3-[2-(2-hydroxyethyl)pyridinium-1-yl]propane-1-sulfonate, TGF-beta receptor type-2
Authors:Wangkanont, K, Forest, K.T, Kiessling, L.L.
Deposit date:2015-01-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201
to be published
5TX4
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Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130
Descriptor: TGF-beta receptor type-2, Transforming growth factor beta-2
Authors:Hinck, A.P, Kim, S.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TY4
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MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution
Descriptor: TGF-beta receptor type-2, mmTGF-b2-7m
Authors:Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T.
Deposit date:2016-11-18
Release date:2017-04-26
Last modified:2023-10-04
Method:ELECTRON CRYSTALLOGRAPHY (2.9 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017

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