PDB: 10 resultsInfo pagesStatus searchChemie searchBIRD

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5TY4	MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution Descriptor: TGF-beta receptor type-2, mmTGF-b2-7m Authors: Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T. Deposit date: 2016-11-18 Release date: 2017-04-26 Last modified: 2023-10-04 Method: ELECTRON CRYSTALLOGRAPHY (2.9 Å) Cite: Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
5TX4	Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130 Descriptor: TGF-beta receptor type-2, Transforming growth factor beta-2 Authors: Hinck, A.P, Kim, S. Deposit date: 2016-11-15 Release date: 2017-03-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.876 Å) Cite: An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling. J. Biol. Chem., 292, 2017
4XJJ	Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201 Descriptor: 3-[2-(2-hydroxyethyl)pyridinium-1-yl]propane-1-sulfonate, TGF-beta receptor type-2 Authors: Wangkanont, K, Forest, K.T, Kiessling, L.L. Deposit date: 2015-01-08 Release date: 2015-06-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201 to be published
4P7U	Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201 Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, TGF-beta receptor type-2 Authors: Wangkanont, K, Forest, K.T. Deposit date: 2014-03-27 Release date: 2015-06-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.502 Å) Cite: The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain. Protein Expr.Purif., 115, 2015
3KFD	Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily Descriptor: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-1 Authors: Radaev, S, Sun, P.D. Deposit date: 2009-10-27 Release date: 2010-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.995 Å) Cite: Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily. J.Biol.Chem., 285, 2010
2PJY	Structural basis for cooperative assembly of the TGF-beta signaling complex Descriptor: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-3 Authors: Groppe, J, Zubieta, C. Deposit date: 2007-04-16 Release date: 2008-02-05 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol.Cell, 29, 2008
1PLO	TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN Descriptor: TGF-beta receptor type II Authors: Deep, S, Walker III, K.P, Shu, Z, Hinck, A.P. Deposit date: 2003-06-08 Release date: 2003-09-23 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: Solution structure and backbone dynamics of the TGF-beta type II receptor extracellular domain Biochemistry, 42, 2003
1M9Z	CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN Descriptor: GLYCEROL, TGF-BETA RECEPTOR TYPE II Authors: Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D. Deposit date: 2002-07-30 Release date: 2002-09-11 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.05 Å) Cite: THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN Structure, 10, 2002
1KTZ	Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3 Descriptor: TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3 Authors: Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P. Deposit date: 2002-01-18 Release date: 2002-02-27 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Nat.Struct.Biol., 9, 2002
1KS6	Transforming Growth Factor Beta type II receptor ligand binding domain Descriptor: TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR Authors: Marlow, M.S, Brown, C.B, Barnett, J.V, Krezel, A.M. Deposit date: 2002-01-10 Release date: 2003-02-25 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of the chick TGFb type II receptor ligand binding domain J.Mol.Biol., 326, 2003