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6X7H
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Cyanovirin-N Mutation I34Y with Dimannose bound
Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
Authors:Fromme, R, Sharma, P, Ghirlanda, G.
Deposit date:2020-05-30
Release date:2021-06-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations.
Elife, 11, 2022
5K79
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Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog
Descriptor: 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER
Authors:Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M.
Deposit date:2016-05-25
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and Glycan Binding of a New Cyanovirin-N Homolog.
J.Biol.Chem., 291, 2016
5C8P
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BU of 5c8p by Molmil
Crystal structure of MoCVNH3 variant (Mo0v) in complex with (N-GlcNAc)3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MoCVNH3 variant
Authors:Koharudin, L.M.I, Gronenborn, A.M.
Deposit date:2015-06-25
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insight into Fungal Cell Wall Recognition by a CVNH Protein with a Single LysM Domain.
Structure, 23, 2015
5C8O
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Crystal structure of MoCVNH3 variant (Mo0v)
Descriptor: MoCVNH3 variant
Authors:Koharudin, L.M.I, Gronenborn, A.M.
Deposit date:2015-06-25
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insight into Fungal Cell Wall Recognition by a CVNH Protein with a Single LysM Domain.
Structure, 23, 2015
5C8Q
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BU of 5c8q by Molmil
Crystal structure of MoCVNH3 variant (Mo0v) in complex with (N-GlcNAc)4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MoCVNH3 variant
Authors:Koharudin, L.M.I, Gronenborn, A.M.
Deposit date:2015-06-25
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insight into Fungal Cell Wall Recognition by a CVNH Protein with a Single LysM Domain.
Structure, 23, 2015
4J4E
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BU of 4j4e by Molmil
Structure of P51G Cyanovirin-N swapped trimer in the P212121 space group
Descriptor: Cyanovirin-N
Authors:Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
Deposit date:2013-02-06
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4G
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Structure of P51G Cyanovirin-N swapped tetramer in the C2 space group
Descriptor: Cyanovirin-N
Authors:Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
Deposit date:2013-02-06
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4F
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BU of 4j4f by Molmil
Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group
Descriptor: Cyanovirin-N
Authors:Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
Deposit date:2013-02-06
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4D
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BU of 4j4d by Molmil
Structure of P51G Cyanovirin-N swapped dimer in the P21212 space group
Descriptor: Cyanovirin-N
Authors:Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
Deposit date:2013-02-06
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4C
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BU of 4j4c by Molmil
Structure of P51G Cyanovirin-N swapped dimer in the P3221 space group
Descriptor: Cyanovirin-N
Authors:Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
Deposit date:2013-02-06
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
3S3Z
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BU of 3s3z by Molmil
Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L10
Descriptor: SODIUM ION, Tandem Cyanovirin-N Dimer CVN2L10
Authors:Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
3S3Y
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BU of 3s3y by Molmil
Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L0
Descriptor: SODIUM ION, TANDEM CYANOVIRIN-N DIMER CVN2L0
Authors:Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
Deposit date:2011-05-18
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YHH
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BU of 2yhh by Molmil
Microvirin:mannobiose complex
Descriptor: MANNAN-BINDING LECTIN, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
Authors:Hussan, S, Bewley, C.A, Clore, G.M, Gustchina, E, Ghirlando, R.
Deposit date:2011-05-02
Release date:2011-06-15
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution Structure of the Monovalent Lectin Microvirin in Complex with Man(Alpha)(1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity.
J.Biol.Chem., 286, 2011
2L9Y
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BU of 2l9y by Molmil
Solution structure of the MoCVNH-LysM module from the rice blast fungus Magnaporthe oryzae protein (MGG_03307)
Descriptor: CVNH-LysM lectin
Authors:Koharudin, L.M.I, Viscomi, A.R, Montanini, B, Kershaw, M.J, Talbot, N.J, Ottonello, S, Gronenborn, A.M.
Deposit date:2011-02-26
Release date:2011-03-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure-Function Analysis of a CVNH-LysM Lectin Expressed during Plant Infection by the Rice Blast Fungus Magnaporthe oryzae.
Structure, 19, 2011
2Y1S
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BU of 2y1s by Molmil
Microvirin lectin
Descriptor: Mannan-binding lectin
Authors:Bewley, C.A, Hussan, S.
Deposit date:2010-12-10
Release date:2011-04-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
J. Biol. Chem., 286, 2011
2L2F
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BU of 2l2f by Molmil
NMR Structure of GzCVNH (Gibberella zeae CVNH)
Descriptor: Cyanovirin-N HOMOLOG
Authors:Matei, E, Louis, J.M, Jee, J.G, Gronenborn, A.M.
Deposit date:2010-08-17
Release date:2011-03-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of a cyanovirin homolog from wheat head blight fungus.
Proteins, 79, 2011
3LHC
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BU of 3lhc by Molmil
Crystal structure of cyanovirin-n swapping domain b mutant
Descriptor: Cyanovirin-N, PHOSPHATE ION, SODIUM ION
Authors:Matei, E, Zheng, A, Furey, W, Rose, J, Aiken, C, Gronenborn, A.M.
Deposit date:2010-01-21
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization.
J.Biol.Chem., 285, 2010
3HP8
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BU of 3hp8 by Molmil
Crystal structure of a designed Cyanovirin-N homolog lectin; LKAMG, bound to sucrose
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cyanovirin-N-like protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Koharudin, L.M.I, Furey, W, Gronenborn, A.M.
Deposit date:2009-06-03
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose binding.
Proteins, 77, 2009
3HNX
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BU of 3hnx by Molmil
Crystal structure of a designed Cyanovirin-N homolog lectin; LKAMG in P212121 space group
Descriptor: Cyanovirin-N-like protein
Authors:Koharudin, L.M.I, Furey, W, Gronenborn, A.M.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:A designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose binding.
Proteins, 77, 2009
3HNU
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BU of 3hnu by Molmil
Crystal structure of a designed Cyanovirin-N homolog lectin; LKAMG in P21 space group
Descriptor: Cyanovirin-N-like protein
Authors:Koharudin, L.M.I, Furey, W, Gronenborn, A.M.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:A designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose binding.
Proteins, 77, 2009
2KJL
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BU of 2kjl by Molmil
NMR structures of a designed Cyanovirin-N homolog lectin; LKAMG
Descriptor: Cyanovirin-N homolog
Authors:Koharudin, L.M.I, Gronenborn, A.M.
Deposit date:2009-05-31
Release date:2009-06-23
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.
Structure, 16, 2008
3GXY
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BU of 3gxy by Molmil
Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
Authors:Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
Deposit date:2009-04-03
Release date:2009-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
3GXZ
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BU of 3gxz by Molmil
Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
Authors:Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
Deposit date:2009-04-03
Release date:2009-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
3CZZ
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BU of 3czz by Molmil
Crystal structure of Cyanovirin-N domain B mutant
Descriptor: Cyanovirin-N
Authors:Matei, E, Furey, W, Gronenborn, A.M.
Deposit date:2008-04-30
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping.
Structure, 16, 2008
2RP3
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BU of 2rp3 by Molmil
Solution Structure of Cyanovirin-N Domain B Mutant
Descriptor: Cyanovirin-N
Authors:Matei, E, Furey, W, Gronenborn, A.M.
Deposit date:2008-04-30
Release date:2008-08-19
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping
Structure, 16, 2008

 

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