5KDI
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HOW FAPP2 SELECTS SIMPLE GLYCOSPHINGOLIPIDS USING THE GLTP-FOLD
Descriptor:Pleckstrin homology domain-containing family A member 8, (~{Z})-~{N}-[(~{E},2~{S},3~{R})-1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-octadec-4-en-2-yl]octadec-9-enamide
Authors:Ochoa-Lizarralde, B., Popov, A.N., Samygina, V.R., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2016-06-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:How FAPP2 Selects Simple Glycosphingolipids Using the GLTP-fold: Structural Insights into Specificity in the GLTP-Family
J.Biol.Chem., 2017
4NTO
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CRYSTAL STRUCTURE OF D60A MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C2 CERAMIDE-1-PHOSPHATE (D18:1/2:0) AT 2.15 ANGSTROM RESOLUTION
Descriptor:accelerated-cell-death 11, (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-12-02
Release date:2014-02-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTI
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CRYSTAL STRUCTURE OF D60N MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C12 CERAMIDE-1-PHOSPHATE (D18:1/12:0) AT 2.9 ANGSTROM RESOLUTION
Descriptor:accelerated-cell-death 11, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-12-02
Release date:2014-02-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NTG
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CRYSTAL STRUCTURE OF D60A MUTANT OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH C12 CERAMIDE-1-PHOSPHATE (D18:1/12:0) AT 2.55 ANGSTROM RESOLUTION
Descriptor:accelerated-cell-death 11, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-12-02
Release date:2014-02-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.5505 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NT2
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CRYSTAL STRUCTURE OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) COMPLEXED WITH LYSO-SPHINGOMYELIN (D18:1) AT 2.4 ANGSTROM RESOLUTION
Descriptor:accelerated-cell-death 11, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, SULFATE ION, ...
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-11-29
Release date:2014-02-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4NT1
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CRYSTAL STRUCTURE OF APO-FORM OF ARABIDOPSIS ACD11 (ACCELERATED-CELL-DEATH 11) AT 1.8 ANGSTROM RESOLUTION
Descriptor:accelerated-cell-death 11, SODIUM ION
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-11-29
Release date:2014-02-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.
Cell Rep, 6, 2014
4KF6
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 8:0 CERAMIDE-1-PHOSPHATE (8:0-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-26
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KBS
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 12:0 PHOSPHATIDIC ACID (12:0 PA)
Descriptor:Glycolipid transfer protein domain-containing protein 1, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-23
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KBR
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CRYSTAL STRUCTURE OF MOUSE CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (APO-FORM)
Descriptor:Glycolipid transfer protein domain-containing protein 1, PHOSPHATE ION
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-23
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K8N
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 18:1 CERAMIDE-1-PHOSPHATE (18:1-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4Z)-3-hydroxy-2-[(9E)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-18
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K85
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 12:0 CERAMIDE-1-PHOSPHATE (12:0-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-17
Release date:2013-07-17
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K84
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 16:0 CERAMIDE-1-PHOSPHATE (16:0-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-17
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K80
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CRYSTAL STRUCTURE OF HUMAN CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN (CPTP) IN COMPLEX WITH 2:0 CERAMIDE-1-PHOSPHATE (2:0-C1P)
Descriptor:Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Authors:Simanshu, D.K., Brown, R.E., Patel, D.J.
Deposit date:2013-04-17
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4H2Z
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE, ...
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Malinina, L.
Deposit date:2012-09-13
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXG
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE (ORTHORHOMBIC FORM; FOUR SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Cabo-Bilbao, A., Goni-de-Cerio, F., Popov, A.N., Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXD
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GVT
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE (HEXAGONAL FORM)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Cabo-Bilbao, A., Goni-de-Cerio, F., Popov, A.N., Malinina, L.
Deposit date:2012-08-31
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GJQ
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE (ORTHORHOMBIC FORM;TWO SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, HEXANE
Authors:Cabo-Bilbao, A., Goni-de-Cerio, F., Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-10
Release date:2013-06-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GIX
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Malinina, L.
Deposit date:2012-08-09
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GHS
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE (ORTHOROMBIC FORM; TWO SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Popov, A.N., Goni-de-Cerio, F., Cabo-Bilbao, A., Malinina, L.
Deposit date:2012-08-08
Release date:2013-06-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GHP
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CRYSTAL STRUCTURE OF D48V||A47D MUTANT OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-08
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GH0
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE
Authors:Samygina, V.R., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-07
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
3S0K
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH GLUCOSYLCERAMIDE CONTAINING OLEOYL ACYL CHAIN (18:1)
Descriptor:Glycolipid transfer protein, (9Z)-N-[(2S,3R,4E)-1-(beta-D-glucopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]octadec-9-enamide, NICKEL (II) ION
Authors:Cabo-Bilbao, A., Samygina, V., Popov, A.N., Ochoa-Lizarralde, B., Goni-de-Cerio, F., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3S0I
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Popov, A.N., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3RZN
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO-GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN (24:1)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-12
Release date:2012-02-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
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