PDB: 15 resultsInfo pagesStatus searchChemie searchBIRD

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1US7	Complex of Hsp90 and P50 Descriptor: HEAT SHOCK PROTEIN HSP82, HSP90 CO-CHAPERONE CDC37 Authors: Roe, S.M, Ali, M.M.U, Pearl, L.H. Deposit date: 2003-11-20 Release date: 2004-01-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Mechanism of Hsp90 Regulation by the Protein Kinase-Specific Cochaperone p50(Cdc37) Cell(Cambridge,Mass.), 116, 2004
7Z38	Structure of the RAF1-HSP90-CDC37 complex (RHC-I) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. Deposit date: 2022-03-01 Release date: 2022-09-14 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
8GAE	Hsp90 provides platform for CRaf dephosphorylation by PP5 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... Authors: Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. Deposit date: 2023-02-22 Release date: 2023-04-26 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
7ZR0	CryoEM structure of HSP90-CDC37-BRAF(V600E) complex. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-14 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7Z37	Structure of the RAF1-HSP90-CDC37 complex (RHC-II) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. Deposit date: 2022-03-01 Release date: 2022-09-14 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
8U1L	Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, Hsp90 co-chaperone Cdc37, ... Authors: Finci, L.I, Simanshu, D.K. Deposit date: 2023-09-01 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7, 2024
8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... Authors: Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. Deposit date: 2023-03-08 Release date: 2023-05-03 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
7ZR5	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
5FWK	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... Authors: Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. Deposit date: 2016-02-17 Release date: 2016-07-06 Last modified: 2019-08-21 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
8FX4	GC-C-Hsp90-Cdc37 regulatory complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Guanylyl cyclase C, Heat shock protein HSP 90-beta, ... Authors: Caveney, N.A, Garcia, K.C. Deposit date: 2023-01-23 Release date: 2023-07-12 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism. Elife, 12, 2023
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-28 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
5FWP	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... Authors: Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. Deposit date: 2016-02-18 Release date: 2016-10-26 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (7.2 Å) Cite: Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWM	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... Authors: Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. Deposit date: 2016-02-18 Release date: 2016-07-06 Last modified: 2019-10-23 Method: ELECTRON MICROSCOPY (8 Å) Cite: Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWL	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... Authors: Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. Deposit date: 2016-02-18 Release date: 2016-07-06 Last modified: 2019-10-23 Method: ELECTRON MICROSCOPY (9 Å) Cite: Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
2N5X	C-terminal domain of Cdc37 cochaperone Descriptor: Hsp90 co-chaperone Cdc37 Authors: Keramisanou, D, Dudhat, A, Pare, M. Deposit date: 2015-08-02 Release date: 2015-10-07 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The C-terminal domain of human Cdc37 studied by solution NMR. J.Biomol.Nmr, 63, 2015