1FWK
 
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, MAGNESIUM ION | | Authors: | Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. | | Deposit date: | 2000-09-22 | | Release date: | 2000-12-20 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
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1FWL
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE | | Descriptor: | HOMOSERINE KINASE | | Authors: | Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. | | Deposit date: | 2000-09-22 | | Release date: | 2000-12-20 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
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1H72
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HOMOSERINE KINASE, L-HOMOSERINE, ... | | Authors: | Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H. | | Deposit date: | 2001-07-02 | | Release date: | 2001-09-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
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1H73
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH THREONINE | | Descriptor: | HOMOSERINE KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, THREONINE | | Authors: | Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H. | | Deposit date: | 2001-07-02 | | Release date: | 2001-09-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
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1H74
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, ISOLEUCINE, ... | | Authors: | Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H. | | Deposit date: | 2001-07-02 | | Release date: | 2001-11-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
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1KKH
 | | Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase | | Authors: | Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C. | | Deposit date: | 2001-12-08 | | Release date: | 2002-03-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
J.Biol.Chem., 277, 2002
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1KVK
 | | The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase | | Authors: | Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J. | | Deposit date: | 2002-01-26 | | Release date: | 2002-03-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Structure of a Binary complex
between a Mammalian Mevalonate Kinase and ATP: Insights into the
Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
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1K47
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1UEK
 | | Crystal structure of 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase | | Descriptor: | 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase | | Authors: | Wada, T, Kuramitsu, S, Yokoyama, S, Tame, J.R.H, Park, S.Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-17 | | Release date: | 2003-06-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis.
J.Biol.Chem., 278, 2003
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1OJ4
 | | Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ... | | Authors: | Miallau, L, Alphey, M.S, Hunter, W.N. | | Deposit date: | 2003-06-30 | | Release date: | 2003-07-31 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
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1PIE
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1VIS
 | | Crystal structure of mevalonate kinase | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Mevalonate kinase | | Authors: | Structural GenomiX | | Deposit date: | 2003-12-01 | | Release date: | 2003-12-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
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1S4E
 | | Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... | | Authors: | Hartley, A, Glynn, S.E, Barynin, V, Baker, P.J, Sedelnikova, S.E, Verhees, C, de Geus, D, van der Oost, J, Timson, D.J, Reece, R.J, Rice, D.W. | | Deposit date: | 2004-01-16 | | Release date: | 2004-04-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
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1WUU
 | | crystal structure of human galactokinase complexed with MgAMPPNP and galactose | | Descriptor: | Galactokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. | | Deposit date: | 2004-12-08 | | Release date: | 2004-12-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA
J.Biol.Chem., 280, 2005
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2A2D
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2A2C
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2AJ4
 | | Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP | | Descriptor: | CHLORIDE ION, Galactokinase, MAGNESIUM ION, ... | | Authors: | Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M. | | Deposit date: | 2005-08-01 | | Release date: | 2005-08-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer
J.Biol.Chem., 280, 2005
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2CZ9
 | | Crystal Structure of galactokinase from Pyrococcus horikoshi | | Descriptor: | CHLORIDE ION, GLYCEROL, Probable galactokinase | | Authors: | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-07-12 | | Release date: | 2006-09-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of galactokinase from Pyrococcus horikoshi
To be Published
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2HFS
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2HFU
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2OI2
 | | Streptococcus pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate | | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, MAGNESIUM ION, Mevalonate kinase | | Authors: | Andreassi, J.L, Bilder, P.W, Vetting, M.W, Roderick, S.L, Leyh, T.S. | | Deposit date: | 2007-01-10 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate.
Protein Sci., 16, 2007
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2DEI
 | | Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PNP and galactose | | Descriptor: | MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Probable galactokinase, alpha-D-galactopyranose | | Authors: | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-02-10 | | Release date: | 2007-05-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of galaktokinase from Pyrococcus horikoshii
To be Published
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2DEJ
 | | Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose | | Descriptor: | Probable galactokinase, alpha-D-galactopyranose, {5'-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM | | Authors: | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-02-10 | | Release date: | 2007-05-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of galaktokinase from Pyrococcus horikoshii
To be Published
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2R42
 | | The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism | | Descriptor: | MAGNESIUM ION, Mevalonate kinase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE | | Authors: | Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. | | Deposit date: | 2007-08-30 | | Release date: | 2008-06-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
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2R3V
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