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7PU7
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BU of 7pu7 by Molmil
DNA polymerase from M. tuberculosis
Descriptor: DNA polymerase III subunit alpha, Template, ZINC ION, ...
Authors:Borsellini, A, Lamers, M.H.
Deposit date:2021-09-28
Release date:2022-02-23
Last modified:2022-04-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis.
Acs Infect Dis., 8, 2022
5LEW
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BU of 5lew by Molmil
DNA polymerase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA polymerase III subunit alpha, SULFATE ION, ...
Authors:Banos-Mateos, S, Lang, U.F, Maslen, S.L, Skehel, J.M, Lamers, M.H.
Deposit date:2016-06-30
Release date:2017-10-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center.
Nat Commun, 8, 2017
5M1S
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BU of 5m1s by Molmil
Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode
Descriptor: DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2016-10-10
Release date:2017-01-18
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
4IQJ
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BU of 4iqj by Molmil
Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Descriptor: DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*GP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DOC))-3'), ...
Authors:Liu, B, Lin, J, Steitz, T.
Deposit date:2013-01-11
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Structure, 21, 2013
4JOM
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BU of 4jom by Molmil
Structure of E. coli Pol III 3mPHP mutant
Descriptor: DNA polymerase III subunit alpha, GLYCEROL, PHOSPHATE ION, ...
Authors:Barros, T, Guenther, J, Kelch, B, Anaya, J, Prabhakar, A, O'Donnell, M, Kuriyan, J, Lamers, M.H.
Deposit date:2013-03-18
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structural role for the PHP domain in E. coli DNA polymerase III.
Bmc Struct.Biol., 13, 2013
5FKU
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BU of 5fku by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA polymerase III alpha, beta, epsilon, tau complex)
Descriptor: DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (8.34 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FKW
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BU of 5fkw by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon)
Descriptor: DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FKV
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BU of 5fkv by Molmil
cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex)
Descriptor: DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (8 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
2HNH
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BU of 2hnh by Molmil
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Meindert, M.H, Georgescu, R.E, Lee, S, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-12
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
2HPI
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BU of 2hpi by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
Descriptor: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ...
Authors:Bailey, S, Wing, R.A, Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
2HPM
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BU of 2hpm by Molmil
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
Descriptor: CHLORIDE ION, DNA Polymerase III alpha subunit, MAGNESIUM ION, ...
Authors:Bailey, S, Wing, R.A, Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
2HQA
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BU of 2hqa by Molmil
Crystal structure of the catalytic alpha subunit of E. Coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Lamers, M.H, Georgescu, R.E, Lee, S.G, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-18
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
3E0D
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BU of 3e0d by Molmil
Insights into the Replisome from the Crystral Structure of the Ternary Complex of the Eubacterial DNA Polymerase III alpha-subunit
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase III subunit alpha, ...
Authors:Wing, R.A, Bailey, S, Steitz, T.A.
Deposit date:2008-07-31
Release date:2008-09-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
J.Mol.Biol., 382, 2008
3F2C
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BU of 3f2c by Molmil
DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP and Mn
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ...
Authors:Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008
3F2D
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BU of 3f2d by Molmil
DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mn and Zn
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ...
Authors:Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008
3F2B
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BU of 3f2b by Molmil
DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mg and Zn
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', ...
Authors:Davies, D.R, Evans, R.J, Bullard, J.M, Christensen, J, Green, L.S, Guiles, J.W, Ribble, W.K, Janjic, N, Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008

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PDB entries from 2024-03-27

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