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8S9P
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1:1:1 agrin/LRP4/MuSK complex
Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
Authors:Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
Deposit date:2023-03-29
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8Q6T
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Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils
Descriptor: Myosin binding protein C, cardiac, Myosin light chain 3, ...
Authors:Tamborrini, D, Raunser, S.
Deposit date:2023-08-14
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structure of the native myosin filament in the relaxed cardiac sarcomere.
Nature, 623, 2023
8P35
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Mutant human titin immunoglobulin-like 21 domain - C3575S
Descriptor: Titin
Authors:Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
Deposit date:2023-05-17
Release date:2023-11-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
8OVU
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Human titin immunoglobulin-like 21 domain
Descriptor: MAGNESIUM ION, Titin
Authors:Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
8K53
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Structure of the Dimeric Human CNTN2 Ig 1-6-FNIII 1-2 Domain in an Asymmetric State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Zhang, Z.Z.
Deposit date:2023-07-21
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
To Be Published
8G4L
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Cryo-EM structure of the human cardiac myosin filament
Descriptor: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ...
Authors:Dutta, D, Nguyen, V, Padron, R, Craig, R.
Deposit date:2023-02-10
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Cryo-EM structure of the human cardiac myosin filament.
Nature, 623, 2023
8BXR
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BU of 8bxr by Molmil
Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-09
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
8A1F
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BU of 8a1f by Molmil
Human PTPRK N-terminal domains MAM-Ig-FN1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E.
Deposit date:2022-06-01
Release date:2023-03-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8A0Y
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BU of 8a0y by Molmil
Crystal structure of mouse contactin 2 immunoglobulin domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2022-05-30
Release date:2023-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Contactin 2 homophilic adhesion structure and conformational plasticity.
Structure, 32, 2024
7ZA3
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GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7ZA2
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GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7ZA1
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BU of 7za1 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7YSW
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BU of 7ysw by Molmil
Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ...
Authors:Mohammadi, M, Chen, L.
Deposit date:2022-08-13
Release date:2023-06-14
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural basis for FGF hormone signalling.
Nature, 618, 2023
7YSU
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Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ...
Authors:Mohammadi, M, Chen, L.
Deposit date:2022-08-13
Release date:2023-04-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for FGF hormone signalling.
Nature, 618, 2023
7YSH
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BU of 7ysh by Molmil
Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, COPPER (II) ION, Fibroblast growth factor 23, ...
Authors:Mohammadi, M, Chen, L.
Deposit date:2022-08-12
Release date:2023-04-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Structural basis for FGF hormone signalling.
Nature, 618, 2023
7YR5
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BU of 7yr5 by Molmil
Embigin facilitates monocarboxylate transporter 1 localization to plasma membrane and transition to a decoupling state
Descriptor: Embigin, Monocarboxylate transporter 1
Authors:Xu, B, Ye, S.
Deposit date:2022-08-08
Release date:2022-09-28
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and transition to a decoupling state.
Cell Rep, 40, 2022
7Y95
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BU of 7y95 by Molmil
Crystal structure of sDscam Ig1 domain, isoform beta6v2
Descriptor: Dscam, GLYCEROL, SODIUM ION
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7TJ7
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BU of 7tj7 by Molmil
Cardiac thin filament decorated with C1 Ig-domain and regulatory M-domain of cardiac myosin binding protein C (cMyBP-C)
Descriptor: Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2022-01-14
Release date:2022-11-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TIT
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BU of 7tit by Molmil
Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor: Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2022-01-14
Release date:2022-11-23
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TIJ
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BU of 7tij by Molmil
Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor: Myosin-binding protein C, cardiac-type, cardiac actin
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2022-01-13
Release date:2022-11-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7SJL
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BU of 7sjl by Molmil
Solution NMR Structure of Immunoglobulin-like Domain of Human Neuregulin-1
Descriptor: Neuregulin-1
Authors:Eletsky, A, Kim, Y, Rogals, M.J, Prestegard, J.H.
Deposit date:2021-10-18
Release date:2022-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling
Commun Biol, 5, 2022
7RAM
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BU of 7ram by Molmil
Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
Descriptor: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
Authors:Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
Deposit date:2021-07-02
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
7R68
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BU of 7r68 by Molmil
Human obscurin Ig12
Descriptor: Obscurin
Authors:Mauriello, G.E, Wright, N.T.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2023-03-22
Method:SOLUTION NMR
Cite:The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
7R67
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BU of 7r67 by Molmil
Human obscurin Ig13
Descriptor: Obscurin
Authors:Moncure, G.E, Wright, N.T.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2023-03-22
Method:SOLUTION NMR
Cite:The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
7OL4
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BU of 7ol4 by Molmil
Mouse contactin-1 neurofascin-155 immunoglobulin domains adhesion complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, Neurofascin, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2021-05-19
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Structural insights into the contactin 1 - neurofascin 155 adhesion complex.
Nat Commun, 13, 2022

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