1EMN
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NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
Descriptor:CALCIUM ION, FIBRILLIN
Authors:Downing, A.K., Campbell, I.D., Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1EMO
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NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES
Descriptor:CALCIUM ION, FIBRILLIN
Authors:Downing, A.K., Campbell, I.D., Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1LMJ
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NMR STUDY OF THE FIBRILLIN-1 CBEGF12-13 PAIR OF CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS
Descriptor:CALCIUM ION, fibrillin 1
Authors:Smallridge, R.S., Whiteman, P., Werner, J.M., Campbell, I.D., Handford, P.A., Downing, A.K.
Deposit date:2002-05-02
Release date:2003-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of a Calcium Binding Epidermal Growth Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1.
J.Biol.Chem., 278, 2003
1Z6C
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SOLUTION STRUCTURE OF AN EGF PAIR (EGF34) FROM VITAMIN K-DEPENDENT PROTEIN S
Descriptor:CALCIUM ION, Vitamin K-dependent protein S
Authors:Drakenberg, T., Ghasriani, H., Thulin, E., Thamlitz, A.M., Muranyi, A., Annila, A., Stenflo, J.
Deposit date:2005-03-22
Release date:2005-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3.
Biochemistry, 44, 2005
2BO2
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EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH CALCIUM.
Descriptor:CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., McDonnell, J.M., Lea, S.M.
Deposit date:2005-04-07
Release date:2006-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOU
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EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH BARIUM.
Descriptor:BARIUM ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., McDonnell, J.M., Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOX
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EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH STRONTIUM.
Descriptor:CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ...
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., McDonnell, J.M., Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2KL7
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SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OF HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICS TARGET HR6275
Descriptor:Fibulin-4
Authors:Rossi, P., Chiang, Y., Anderson, S., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-30
Release date:2009-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
To be Published
5KY0
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MOUSE POFUT1 IN COMPLEX WITH MOUSE NOTCH1 EGF12(D464G) AND GDP
Descriptor:GDP-fucose protein O-fucosyltransferase 1, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Li, Z., Rini, J.M.
Deposit date:2016-07-20
Release date:2017-05-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
Nat. Chem. Biol., 13, 2017
5KY8
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MOUSE POFUT1 IN COMPLEX WITH O-GLUCOSYLATED MOUSE NOTCH1 EGF12 MUTANT (D464G) AND GDP
Descriptor:BETA-D-GLUCOSE, GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Li, Z., Rini, J.M.
Deposit date:2016-07-21
Release date:2017-05-17
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
Nat. Chem. Biol., 13, 2017
5KY9
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MOUSE POFUT1 IN COMPLEX WITH MOUSE NOTCH1 EGF12 MUTANT (D464G/A465G) AND GDP
Descriptor:GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Li, Z., Rini, J.M.
Deposit date:2016-07-21
Release date:2017-05-17
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
Nat. Chem. Biol., 13, 2017
1NT0
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CRYSTAL STRUCTURE OF THE CUB1-EGF-CUB2 REGION OF MASP2
Descriptor:1,2-ETHANEDIOL, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Feinberg, H., Uitdehaag, J.C.M., Davies, J.M., Wallis, R., Drickamer, K., Weis, W.I.
Deposit date:2003-01-28
Release date:2003-05-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Embo J., 22, 2003
1SZB
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CRYSTAL STRUCTURE OF THE HUMAN MBL-ASSOCIATED PROTEIN 19 (MAP19)
Descriptor:CALCIUM ION, mannose binding lectin-associated serine protease-2 related protein, MAp19 (19kDa)
Authors:Gregory, L.A., Thielens, N.M., Arlaud, G.J., Fontecilla-Camps, J.C., Gaboriaud, C.
Deposit date:2004-04-05
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin
J.Biol.Chem., 279, 2004
1TOZ
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NMR STRUCTURE OF THE HUMAN NOTCH-1 LIGAND BINDING REGION
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Hambleton, S., Valeyev, N.Y., Muranyi, A., Knott, V., Werner, J.M., Mcmichael, A.J., Handford, P.A., Downing, A.K.
Deposit date:2004-06-15
Release date:2004-10-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12, 2004
1UZJ
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INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, HOLO FORM.
Descriptor:CALCIUM ION, FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-12
Release date:2004-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZK
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INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, CA BOUND TO CBEGF23 DOMAIN ONLY
Descriptor:CALCIUM ION, FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-13
Release date:2006-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZP
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INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, SM BOUND FORM CBEGF23 DOMAIN ONLY.
Descriptor:FIBRILLIN-1, SAMARIUM (III) ION
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZQ
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INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, APO FORM CBEGF23 DOMAIN ONLY.
Descriptor:FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1YO8
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STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN THROMBOSPONDIN-2
Descriptor:ALPHA-D-MANNOSE, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Carlson, C.B., Bernstein, D.A., Annis, D.S., Misenheimer, T.M., Hannah, B.A., Mosher, D.F., Keck, J.L.
Deposit date:2005-01-26
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the calcium-rich signature domain of human thrombospondin-2
Nat.Struct.Mol.Biol., 12, 2005
2RHP
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THE THROMBOSPONDIN-1 POLYMORPHISM ASN700SER ASSOCIATED WITH CORNOARY ARTERY DISEASE CAUSES LOCAL AND LONG-RANGING CHANGES IN PROTEIN STRUCTURE
Descriptor:CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, Thrombospondin-2
Authors:Carlson, C.B., Keck, J.L., Mosher, D.F.
Deposit date:2007-10-09
Release date:2008-05-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability.
J.Biol.Chem., 283, 2008
2VJ3
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HUMAN NOTCH-1 EGFS 11-13
Descriptor:CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ...
Authors:Johnson, S., Cordle, J., Tay, J.Z., Roversi, P., Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
2W86
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CRYSTAL STRUCTURE OF FIBRILLIN-1 DOMAINS CBEGF9HYB2CBEGF10, CALCIUM SATURATED FORM
Descriptor:CALCIUM ION, FIBRILLIN-1, IODIDE ION
Authors:Jensen, S.A., Iqbal, S., Lowe, E.D., Redfield, C., Handford, P.A.
Deposit date:2009-01-09
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17, 2009
4CUD
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT FUCOSYLATED AT T466
Descriptor:ALPHA-L-FUCOSE, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S., Haltiwanger, R., Handford, P.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CUE
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466V
Descriptor:CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S., Haltiwanger, R., Handford, P.
Deposit date:2014-03-18
Release date:2014-05-21
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CUF
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HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466S
Descriptor:1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S., Haltiwanger, R., Handford, P.
Deposit date:2014-03-18
Release date:2014-05-14
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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