3BXZ
 
 | | Crystal structure of the isolated DEAD motor domains from Escherichia coli SecA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Preprotein translocase subunit secA, ... | | Authors: | Nithianantham, S, Namjoshi, S, Shilton, B.H. | | Deposit date: | 2008-01-15 | | Release date: | 2008-09-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Analysis of the isolated SecA DEAD motor suggests a mechanism for chemical-mechanical coupling.
J.Mol.Biol., 383, 2008
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4YS0
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6ITC
 | | Structure of a substrate engaged SecA-SecY protein translocation machine | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Ma, C.Y, Wu, X.F, Sun, D.J, Park, E.Y, Rapoport, T.A, Gao, N, Long, L. | | Deposit date: | 2018-11-21 | | Release date: | 2019-06-12 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structure of the substrate-engaged SecA-SecY protein translocation machine.
Nat Commun, 10, 2019
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5EUL
 | | Structure of the SecA-SecY complex with a translocating polypeptide substrate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AYC08, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Li, L, Park, E, Ling, J, Ingram, J, Ploegh, H, Rapoport, T.A. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-09 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Crystal structure of a substrate-engaged SecY protein-translocation channel.
Nature, 531, 2016
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4UAQ
 | | Crystal structure of the accessory translocation ATPase, SecA2, from Mycobacterium tuberculosis | | Descriptor: | Protein translocase subunit SecA 2 | | Authors: | Swanson-Smith, S, Ioerger, T.R, Rigel, N.W, Miller, B.K, Braunstein, M, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2014-08-11 | | Release date: | 2015-09-09 | | Last modified: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Similarities and Differences between Two Functionally Distinct SecA Proteins, Mycobacterium tuberculosis SecA1 and SecA2.
J.Bacteriol., 198, 2015
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6GOX
 | | SecA | | Descriptor: | Protein translocase subunit SecA | | Authors: | White, S.A, Huber, D. | | Deposit date: | 2018-06-04 | | Release date: | 2019-06-19 | | Last modified: | 2020-07-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity.
Elife, 8, 2019
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2VDA
 | | Solution structure of the SecA-signal peptide complex | | Descriptor: | MALTOPORIN, TRANSLOCASE SUBUNIT SECA | | Authors: | Gelis, I, Bonvin, A.M.J.J, Keramisanou, D, Koukaki, M, Gouridis, G, Karamanou, S, Economou, A, Kalodimos, C.G. | | Deposit date: | 2007-10-01 | | Release date: | 2007-11-27 | | Last modified: | 2018-01-24 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Signal-Sequence Recognition by the Translocase Motor Seca as Determined by NMR
Cell(Cambridge,Mass.), 131, 2007
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2IBM
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2IPC
 | | Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer | | Descriptor: | Preprotein translocase SecA subunit | | Authors: | Vassylyev, D.G, Mori, H, Vassylyeva, M.N, Tsukazaki, T, Kimura, Y, Tahirov, T.H, Ito, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-10-12 | | Release date: | 2006-11-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer.
J.Mol.Biol., 364, 2006
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7XHA
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7XHB
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5K94
 | | Deletion-Insertion Chimera of MBP with the Preprotein Cross-Linking Domain of the SecA ATPase | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Maltose-binding periplasmic protein,Protein translocase subunit SecA,Maltose-binding periplasmic protein | | Authors: | Shilton, B.H, Hackett, J, Ghonaim, N. | | Deposit date: | 2016-05-31 | | Release date: | 2017-06-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of a polypeptide-binding site in the DEAD Motor of the SecA ATPase.
FEBS Lett., 591, 2017
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5K9T
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1TF2
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1TF5
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6S0K
 | | Ribosome nascent chain in complex with SecA | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | | Authors: | Jomaa, A, Wang, S, Shan, S, Ban, N. | | Deposit date: | 2019-06-17 | | Release date: | 2019-10-09 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA.
Nat.Struct.Mol.Biol., 26, 2019
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3DL8
 | | Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | | Descriptor: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | | Authors: | Nam, Y, Zimmer, J, Rapoport, T.A. | | Deposit date: | 2008-06-26 | | Release date: | 2008-12-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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3DIN
 | | Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Zimmer, J, Nam, Y, Rapoport, T.A. | | Deposit date: | 2008-06-20 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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6SXH
 | | Crystal structure of the accessory translocation ATPase, SecA2, from Clostridium difficile | | Descriptor: | Protein translocase subunit SecA 2 | | Authors: | Lindic, N, Loboda, J, Usenik, A, Turk, D. | | Deposit date: | 2019-09-26 | | Release date: | 2020-10-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the accessory translocation ATPase, SecA2, from Clostridium difficile
To Be Published
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6T4H
 | | Crystal structure of the accessory translocation ATPase, SecA2, from Clostridium difficile, in complex with adenosine-5'-(gamma-thio)-triphosphate | | Descriptor: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Protein translocase subunit SecA 2 | | Authors: | Lindic, N, Loboda, J, Usenik, A, Turk, D. | | Deposit date: | 2019-10-14 | | Release date: | 2020-11-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The Structure of Clostridioides difficile SecA2 ATPase Exposes Regions Responsible for Differential Target Recognition of the SecA1 and SecA2-Dependent Systems.
Int J Mol Sci, 21, 2020
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3IQY
 | | Active site mutants of B. subtilis SecA | | Descriptor: | Protein translocase subunit secA, SULFATE ION | | Authors: | Kim, D, Hunt, J.F. | | Deposit date: | 2009-08-21 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | ATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA Translocase.
J.Am.Chem.Soc., 135, 2013
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3IQM
 | | Active site mutants of B. subtilis SecA | | Descriptor: | Protein translocase subunit secA, SULFATE ION | | Authors: | Kim, D, Hunt, J.F. | | Deposit date: | 2009-08-20 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | ATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA Translocase.
J.Am.Chem.Soc., 135, 2013
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3JUX
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3JV2
 | | Crystal Structure of B. subtilis SecA with bound peptide | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA, ... | | Authors: | Zimmer, J. | | Deposit date: | 2009-09-15 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Conformational flexibility and peptide interaction of the translocation ATPase SecA.
J.Mol.Biol., 394, 2009
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1M74
 | | Crystal structure of Mg-ADP-bound SecA from Bacillus subtilis | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Preprotein translocase secA, ... | | Authors: | Hunt, J.F, Weinkauf, S, Henry, L, Fak, J.J, McNicholas, P, Oliver, D.B, Deisenhofer, J. | | Deposit date: | 2002-07-16 | | Release date: | 2002-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Nucleotide Control of Interdomain Interactions in the Conformational Reaction Cycle of SecA
Science, 297, 2002
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