3W0F
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CRYSTAL STRUCTURE OF MOUSE ENDONUCLEASE VIII-LIKE 3 (MNEIL3)
Descriptor:Endonuclease 8-like 3, ZINC ION, IODIDE ION
Authors:Liu, M., Imamura, K., Averill, A.M., Wallace, S.S., Doublie, S.
Deposit date:2012-10-30
Release date:2013-01-16
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA
Structure, 21, 2013
4MB7
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CRYSTAL STRUCTURE OF A VIRAL DNA GLYCOSYLASE
Descriptor:Endonuclease 8-like L720, ZINC ION, SULFATE ION
Authors:Prakash, A., Eckenroth, B.E., Doublie, S.
Deposit date:2013-08-19
Release date:2013-10-30
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases.
Dna Repair, 12, 2013
4NRW
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MVNEI1-G86D
Descriptor:formamidopyrimidine-DNA glycosylase, 5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'
Authors:Prakash, A., Doublie, S.
Deposit date:2013-11-27
Release date:2014-01-01
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.845 Å)
Cite:Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing.
Dna Repair, 14, 2014
1EE8
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CRYSTAL STRUCTURE OF MUTM (FPG) PROTEIN FROM THERMUS THERMOPHILUS HB8
Descriptor:MUTM (FPG) PROTEIN, ZINC ION
Authors:Sugahara, M., Mikawa, T., Kumasaka, T., Yamamoto, M., Kato, R., Fukuyama, K., Inoue, Y., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2000-01-31
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8.
EMBO J., 19, 2000
1K3W
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CRYSTAL STRUCTURE OF A TRAPPED REACTION INTERMEDIATE OF THE DNA REPAIR ENZYME ENDONUCLEASE VIII WITH DNA
Descriptor:5'-D(*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*GP*G)-3', 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', Endonuclease VIII, ...
Authors:Golan, G., Zharkov, D.O., Gilboa, R., Fernandes, A.S., Kycia, J.H., Gerchman, S.E., Rieger, R.A., Grollman, A.P., Shoham, G.
Deposit date:2001-10-04
Release date:2002-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.
EMBO J., 21, 2002
1K3X
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CRYSTAL STRUCTURE OF A TRAPPED REACTION INTERMEDIATE OF THE DNA REPAIR ENZYME ENDONUCLEASE VIII WITH BROMINATED-DNA
Descriptor:5'-D(*GP*GP*CP*(BRU)P*(BRU)P*CP*AP*(BRU)P*CP*CP*(BRU)P*GP*G)-3', 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', Endonuclease VIII, ...
Authors:Golan, G., Zharkov, D.O., Gilboa, R., Fernandes, A.S., Kycia, J.H., Gerchman, S.E., Rieger, R.A., Grollman, A.P., Shoham, G.
Deposit date:2001-10-04
Release date:2002-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.
EMBO J., 21, 2002
1K82
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CRYSTAL STRUCTURE OF E.COLI FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FPG) COVALENTLY TRAPPED WITH DNA
Descriptor:5'-D(*GP*GP*CP*TP*TP*CP*CP*TP*CP*CP*TP*GP*G)-3', 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', formamidopyrimidine-DNA glycosylase, ...
Authors:Gilboa, R., Zharkov, D.O., Golan, G., Fernandes, A.S., Gerchman, S.E., Matz, E., Kycia, J.H., Grollman, A.P., Shoham, G.
Deposit date:2001-10-22
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.
J.Biol.Chem., 277, 2002
1KFV
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CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS FORMAMIDO-PYRIMIDINE DNA GLYCOSYLASE (ALIAS FPG OR MUTM) NON COVALENTLY BOUND TO AN AP SITE CONTAINING DNA.
Descriptor:5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*G)-3', Formamido-pyrimidine DNA glycosylase, ...
Authors:Serre, L., Pereira de Jesus, K., Boiteux, S., Zelwer, C., Castaing, B.
Deposit date:2001-11-23
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA.
EMBO J., 21, 2002
1L1T
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MUTM (FPG) BOUND TO ABASIC-SITE CONTAINING DNA
Descriptor:5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2002-02-19
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L1Z
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MUTM (FPG) COVALENT-DNA INTERMEDIATE
Descriptor:5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2002-02-20
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L2B
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MUTM (FPG) DNA END-PRODUCT STRUCTURE
Descriptor:5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*C*(AD2))-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2002-02-20
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L2C
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MUTM (FPG)-DNA ESTRANGED THYMINE MISMATCH RECOGNITION COMPLEX
Descriptor:5'-D(*AP*G*GP*TP*AP*GP*AP*CP*TP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2002-02-20
Release date:2002-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1NNJ
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CRYSTAL STRUCTURE COMPLEX BETWEEN THE LACTOCOCCUS LACTIS FPG AND AN ABASIC SITE CONTAINING DNA
Descriptor:5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ...
Authors:Serre, L., Pereira de Jesus, K., Boiteux, S., Zelwer, C., Castaing, B.
Deposit date:2003-01-14
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PJI
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CRYSTAL STRUCTURE OF WILD TYPE LACTOCOCCUS LACTIS FPG COMPLEXED TO A 1,3 PROPANEDIOL CONTAINING DNA
Descriptor:DNA (5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
Authors:Pereira, K., Serre, L., Zelwer, C., Castaing, B.
Deposit date:2003-06-03
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PJJ
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COMPLEX BETWEEN THE LACTOCOCCUS LACTIS FPG AND AN ABASIC SITE CONTAINING DNA.
Descriptor:DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
Authors:Serre, L., Pereira de Jesus, K., Boiteux, S., Zelwer, C., Castaing, B.
Deposit date:2003-06-03
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PM5
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CRYSTAL STRUCTURE OF WILD TYPE LACTOCOCCUS LACTIS FPG COMPLEXED TO A TETRAHYDROFURAN CONTAINING DNA
Descriptor:DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
Authors:Pereira de Jesus-Tran, K., Serre, L., Zelwer, C., Castaing, B.
Deposit date:2003-06-10
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1Q39
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CRYSTAL STRUCTURE OF THE DNA REPAIR ENZYME ENDONUCLEASE-VIII (NEI) FROM E. COLI: THE WT ENZYME AT 2.8 RESOLUTION.
Descriptor:Endonuclease VIII, ZINC ION, CALCIUM ION
Authors:Golan, G., Zharkov, D.O., Feinberg, H., Fernandes, A.S., Zaika, E.I., Kycia, J.H., Grollman, A.P., Shoham, G.
Deposit date:2003-07-29
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1Q3B
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CRYSTAL STRUCTURE OF THE DNA REPAIR ENZYME ENDONUCLEASE-VIII (NEI) FROM E. COLI: THE R252A MUTANT AT 2.05 RESOLUTION.
Descriptor:Endonuclease VIII, ZINC ION, MAGNESIUM ION, ...
Authors:Golan, G., Zharkov, D.O., Feinberg, H., Fernandes, A.S., Zaika, E.I., Kycia, J.H., Grollman, A.P., Shoham, G.
Deposit date:2003-07-29
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1Q3C
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CRYSTAL STRUCTURE OF THE DNA REPAIR ENZYME ENDONUCLEASE-VIII (NEI) FROM E. COLI: THE E2A MUTANT AT 2.3 RESOLUTION.
Descriptor:Endonuclease VIII, ZINC ION, MAGNESIUM ION, ...
Authors:Golan, G., Zharkov, D.O., Feinberg, H., Fernandes, A.S., Zaika, E.I., Kycia, J.H., Grollman, A.P., Shoham, G.
Deposit date:2003-07-29
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1R2Y
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MUTM (FPG) BOUND TO 8-OXOGUANINE (OXOG) CONTAINING DNA
Descriptor:5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2003-09-30
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:DNA Lesion Recognition by the Bacterial Repair Enzyme MutM.
J.Biol.Chem., 278, 2003
1R2Z
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MUTM (FPG) BOUND TO 5,6-DIHYDROURACIL (DHU) CONTAINING DNA
Descriptor:5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(DHU)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C., Verdine, G.L.
Deposit date:2003-09-30
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:DNA Lesion Recognition by the Bacterial Repair Enzyme MutM.
J.Biol.Chem., 278, 2003
1TDZ
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CRYSTAL STRUCTURE COMPLEX BETWEEN THE LACTOCOCCUS LACTIS FPG (MUTM) AND A FAPY-DG CONTAINING DNA
Descriptor:5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', formamidopyrimidine-DNA glycosylase, ...
Authors:Coste, F., Ober, M., Carell, T., Boiteux, S., Zelwer, C., Castaing, B.
Deposit date:2004-05-24
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase
J.Biol.Chem., 279, 2004
1XC8
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CRYSTAL STRUCTURE COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND A FAPY-DG CONTAINING DNA
Descriptor:5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ...
Authors:Coste, F., Ober, M., Carell, T., Boiteux, S., Zelwer, C., Castaing, B.
Deposit date:2004-09-01
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase.
J.Biol.Chem., 279, 2004
2EA0
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CRYSTAL STRUCTURE OF THE DNA REPAIR ENZYME ENDONUCLEASE-VIII (NEI) FROM E. COLI IN COMPLEX WITH AP-SITE CONTAINING DNA SUBSTRATE
Descriptor:5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', Endonuclease VIII, ...
Authors:Golan, G., Zharov, D.O., Grollman, A.P., Shoham, G.
Deposit date:2007-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrate and mutations of critical residues
To be Published
2F5N
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MUTM CROSSLINKED TO UNDAMAGED DNA SAMPLING A:T BASE PAIR IC1
Descriptor:5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', formamidopyrimidine-DNA glycosidase, ...
Authors:Banerjee, A., Santos, W.L., Verdine, G.L.
Deposit date:2005-11-26
Release date:2006-03-07
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a DNA glycosylase searching for lesions.
Science, 311, 2006
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