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1FU1
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CRYSTAL STRUCTURE OF HUMAN XRCC4
Descriptor: ACETIC ACID, DNA REPAIR PROTEIN XRCC4
Authors:Junop, M, Modesti, M, Guarne, A, Gellert, M, Yang, W.
Deposit date:2000-09-13
Release date:2000-12-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Xrcc4 DNA repair protein and implications for end joining.
EMBO J., 19, 2000
1IK9
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CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX
Descriptor: DNA LIGASE IV, DNA REPAIR PROTEIN XRCC4
Authors:Sibanda, B.L, Critchlow, S.E, Begun, J, Pei, X.Y, Jackson, S.P, Blundell, T.L, Pellegrini, L.
Deposit date:2001-05-03
Release date:2001-11-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an Xrcc4-DNA ligase IV complex.
Nat.Struct.Biol., 8, 2001
3II6
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Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
Descriptor: CHLORIDE ION, DNA ligase 4, DNA repair protein XRCC4
Authors:Meesala, S, Junop, M.
Deposit date:2009-07-31
Release date:2009-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4
MOL.CELL.BIOL., 11, 2009
3MUD
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BU of 3mud by Molmil
Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle
Descriptor: 1,2-ETHANEDIOL, DNA repair protein XRCC4,Tropomyosin alpha-1 chain, SULFATE ION, ...
Authors:Klenchin, V.A, Frye, J, Rayment, I.
Deposit date:2010-05-02
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition .
Biochemistry, 49, 2010
3Q4F
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BU of 3q4f by Molmil
Crystal structure of xrcc4/xlf-cernunnos complex
Descriptor: DNA repair protein XRCC4, Non-homologous end-joining factor 1
Authors:Ropars, V, Legrand, P, Charbonnier, J.B.
Deposit date:2010-12-23
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RWR
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Crystal structure of the human XRCC4-XLF complex
Descriptor: DNA repair protein XRCC4, HEXATANTALUM DODECABROMIDE, Non-homologous end-joining factor 1
Authors:Andres, S.N, Junop, M.S.
Deposit date:2011-05-09
Release date:2011-12-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.943 Å)
Cite:Structure of human XLF-XRCC4: assembly of a functional DNA repair complex
To be Published
3SR2
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Crystal Structure of Human XLF-XRCC4 Complex
Descriptor: DNA repair protein XRCC4, Non-homologous end-joining factor 1
Authors:Hammel, M, Classen, S, Tainer, J.A.
Deposit date:2011-07-06
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.9708 Å)
Cite:XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair.
J.Biol.Chem., 286, 2011
3W03
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BU of 3w03 by Molmil
XLF-XRCC4 complex
Descriptor: DNA repair protein XRCC4, Non-homologous end-joining factor 1
Authors:Wu, Q, Ochi, T, Matak-Vinkovic, D, Robinson, C.V, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2012-10-17
Release date:2012-11-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (8.492 Å)
Cite:Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions
Biochem.Soc.Trans., 39, 2011
4XA4
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Crystal Structure of the coiled-coil surrounding Skip 3 of MYH7
Descriptor: Xrcc4-MYH7(1551-1609) chimera protein
Authors:Taylor, K.C, Buvoli, M, Korkmaz, E.N, Buvoli, A, Zheng, Y, Heinz, N.T, Qiang, C, Leinwand, L.A, Rayment, I.
Deposit date:2014-12-12
Release date:2015-07-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.327 Å)
Cite:Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CHX
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Crystal Structure of amino acids 1590-1657 of MYH7
Descriptor: Xrcc4-MYH7-1590-1657
Authors:Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinz, N.T, Cui, Q, Rayment, I.
Deposit date:2015-07-10
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
5CJ0
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Crystal Structure of Amino Acids 1631-1692 of MYH7
Descriptor: Xrcc4-MYH7-(1631-1692) chimera protein
Authors:Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I.
Deposit date:2015-07-13
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
5CJ4
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Crystal Structure of Amino Acids 1562-1622 of MYH7
Descriptor: Xrcc4-MYH7-(1562-1622) chimera protein
Authors:Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I.
Deposit date:2015-07-13
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
5WJ7
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BU of 5wj7 by Molmil
Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4
Descriptor: DNA repair protein XRCC4,Myosin-7
Authors:Andreas, M.P, Ajay, G, Gellings, J, Rayment, I.
Deposit date:2017-07-21
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod.
J. Struct. Biol., 200, 2017
5WLZ
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BU of 5wlz by Molmil
Crystal Structure of Amino Acids 1677-1758 of Human Beta Cardiac Myosin Fused to Xrcc4
Descriptor: DNA repair protein XRCC4,Myosin-7
Authors:Andreas, M.P, Ajay, G, Gellings, J, Rayment, I.
Deposit date:2017-07-28
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod.
J. Struct. Biol., 200, 2017
6ABO
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BU of 6abo by Molmil
human XRCC4 and IFFO1 complex
Descriptor: DNA repair protein XRCC4, GLYCEROL, Intermediate filament family orphan 1, ...
Authors:Li, J, Liu, L, Liang, H, Liu, Y, Xu, D.
Deposit date:2018-07-23
Release date:2019-07-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis.
Nat.Cell Biol., 21, 2019
7LSY
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BU of 7lsy by Molmil
NHEJ Short-range synaptic complex
Descriptor: DNA (26-MER), DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3'), ...
Authors:He, Y, Chen, S.
Deposit date:2021-02-18
Release date:2021-04-14
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
7LT3
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BU of 7lt3 by Molmil
NHEJ Long-range synaptic complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ...
Authors:He, Y, Chen, S.
Deposit date:2021-02-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
7M3P
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BU of 7m3p by Molmil
Xrcc4-Spc110p(164-207) fusion
Descriptor: Xrcc4-Spc110p(164-207)
Authors:Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
Deposit date:2021-03-18
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.0000186 Å)
Cite:CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7NFC
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BU of 7nfc by Molmil
Cryo-EM structure of NHEJ super-complex (dimer)
Descriptor: DNA (27-MER), DNA (28-MER), DNA ligase 4, ...
Authors:Chaplin, A.K, Hardwick, S.W, Kefala Stavridi, A, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2021-02-05
Release date:2021-08-18
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
Mol.Cell, 81, 2021
7NFE
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BU of 7nfe by Molmil
Cryo-EM structure of NHEJ super-complex (monomer)
Descriptor: DNA (5'-D(P*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*CP*TP*AP*TP*TP*AP*TP*TP*AP*TP*G)-3'), DNA (5'-D(P*TP*AP*AP*TP*AP*AP*TP*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*AP*G)-3'), DNA ligase 4, ...
Authors:Chaplin, A.K, Hardwick, S.W, Kefala Stavridi, A, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2021-02-06
Release date:2021-08-18
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
Mol.Cell, 81, 2021
8BH3
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BU of 8bh3 by Molmil
DNA-PK Ku80 mediated dimer bound to PAXX
Descriptor: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
Authors:Hardwick, S.W, Chaplin, A.K.
Deposit date:2022-10-28
Release date:2023-06-07
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BHV
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BU of 8bhv by Molmil
DNA-PK XLF mediated dimer bound to PAXX
Descriptor: DNA (24-MER), DNA (26-MER), DNA (27-MER), ...
Authors:Hardwick, S.W, Chaplin, A.K.
Deposit date:2022-11-01
Release date:2023-06-07
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.51 Å)
Cite:PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BHY
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BU of 8bhy by Molmil
DNA-PK Ku80 mediated dimer bound to PAXX and XLF
Descriptor: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
Authors:Hardwick, S.W, Chaplin, A.K.
Deposit date:2022-11-01
Release date:2023-06-07
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (5.33 Å)
Cite:PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BOT
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BU of 8bot by Molmil
Cryo-EM structure of NHEJ supercomplex(trimer)
Descriptor: DNA (24-MER), DNA (27-MER), DNA (28-MER), ...
Authors:Hardwick, S.W, Chaplin, A.K.
Deposit date:2022-11-15
Release date:2023-06-28
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (7.76 Å)
Cite:Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.
Structure, 31, 2023
8EZA
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BU of 8eza by Molmil
NHEJ Long-range complex with PAXX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (30-MER), DNA (31-MER), ...
Authors:Chen, S, He, Y.
Deposit date:2022-10-31
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ.
Sci Adv, 9, 2023

 

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