PDB: 11 resultsInfo pagesStatus searchChemie searchBIRD

---

8POI	Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine Descriptor: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30 Authors: Borggraefe, J, Gaussmann, S, Sattler, M. Deposit date: 2023-07-04 Release date: 2023-08-23 Last modified: 2023-08-30 Method: SOLUTION NMR Cite: Pharmacological perturbation of the phase-separating protein SMNDC1. Nat Commun, 14, 2023
7W30	Tudor domain of SMN in complex with a small molecule Descriptor: 1,2-dimethylquinolin-4-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION Authors: Li, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Liu, Y, Min, J. Deposit date: 2021-11-24 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
7W2P	Tudor domain of SMN in complex with a small molecule Descriptor: 2-[(4-fluorophenyl)methyl]-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),3(7)-dien-8-imine, MAGNESIUM ION, Survival motor neuron protein, ... Authors: Li, W, Arrowsmith, C.H, Edwards, A.M, Liu, Y, Min, J. Deposit date: 2021-11-24 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.15 Å) Cite: A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
4QQ6	Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule Descriptor: 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION Authors: Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2014-06-26 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
4V98	The 8S snRNP Assembly Intermediate Descriptor: CG10419, Icln, LD23602p, ... Authors: Grimm, C, Pelz, J.P, Schindelin, H, Diederichs, K, Kuper, J, Kisker, C. Deposit date: 2012-05-15 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural Basis of Assembly Chaperone- Mediated snRNP Formation. Mol.Cell, 49, 2013
4A4F	Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine Descriptor: N3, N4-DIMETHYLARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 Authors: Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. Deposit date: 2011-10-12 Release date: 2011-11-30 Last modified: 2018-04-11 Method: SOLUTION NMR Cite: Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
4A4E	Solution structure of SMN Tudor domain in complex with symmetrically dimethylated arginine Descriptor: N3, N4-DIMETHYLARGININE, SURVIVAL MOTOR NEURON PROTEIN Authors: Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. Deposit date: 2011-10-12 Release date: 2011-11-30 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
4A4H	Solution structure of SPF30 Tudor domain in complex with asymmetrically dimethylated arginine Descriptor: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 Authors: Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. Deposit date: 2011-10-12 Release date: 2011-11-30 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
4A4G	Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine Descriptor: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN Authors: Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M. Deposit date: 2011-10-12 Release date: 2011-11-30 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins Nat.Struct.Mol.Biol., 18, 2011
1MHN	High resolution crystal structure of the SMN Tudor domain Descriptor: Survival motor neuron protein Authors: Sprangers, R, Groves, M.R, Sinning, I, Sattler, M. Deposit date: 2002-08-20 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: High Resolution X-ray and NMR Structures of the SMN Tudor Domain: conformational variation in the binding site for symmetrically dimethylated arginine residues J.Mol.Biol., 327, 2003
1G5V	SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN Descriptor: SURVIVAL MOTOR NEURON PROTEIN 1 Authors: Selenko, P, Sprangers, R, Stier, G, Buehler, D, Fischer, U, Sattler, M. Deposit date: 2000-11-02 Release date: 2001-05-02 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: SMN tudor domain structure and its interaction with the Sm proteins. Nat.Struct.Biol., 8, 2001