3JBL
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CRYO-EM STRUCTURE OF THE ACTIVATED NAIP2/NLRC4 INFLAMMASOME REVEALS NUCLEATED POLYMERIZATION
Descriptor:NLR family CARD domain-containing protein 4
Authors:Zhang, L., Chen, S., Ruan, J., Wu, J., Tong, A.B., Yin, Q., Li, Y., David, L., Lu, A., Wang, W.L., Marks, C., Ouyang, Q., Zhang, X., Mao, Y., Wu, H.
Deposit date:2015-09-05
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
5IRL
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CRYSTAL STRUCTURE OF RABBIT NOD2 SER MUTANT IN AN ADP-BOUND STATE
Descriptor:Uncharacterized protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Maekawa, S., Ohto, U., Shimizu, T.
Deposit date:2016-03-14
Release date:2016-06-29
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal structure of NOD2 and its implications in human disease.
Nat Commun, 7, 2016
5IRM
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CRYSTAL STRUCTURE OF RABBIT NOD2 IN AN ADP-BOUND STATE (CRYSTAL FORM2)
Descriptor:Uncharacterized protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Maekawa, S., Ohto, U., Shimizu, T.
Deposit date:2016-03-14
Release date:2016-06-29
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Crystal structure of NOD2 and its implications in human disease.
Nat Commun, 7, 2016
5IRN
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CRYSTAL STRUCTURE OF RABBIT NOD2 IN AN ADP-BOUND STATE (CRYSTAL FORM1)
Descriptor:Uncharacterized protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Maekawa, S., Ohto, U., Shimizu, T.
Deposit date:2016-03-14
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of NOD2 and its implications in human disease.
Nat Commun, 7, 2016
4KXF
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CRYSTAL STRUCTURE OF NLRC4 REVEALS ITS AUTOINHIBITION MECHANISM
Descriptor:NLR family CARD domain-containing protein 4, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:Chai, J., Hu, Z.
Deposit date:2013-05-25
Release date:2013-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of NLRC4 reveals its autoinhibition mechanism
Science, 341, 2013
5AJ2
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CRYO ELECTRON TOMOGRAPHY OF THE NAIP5-NLRC4 INFLAMMASOME
Descriptor:NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4
Authors:Diebolder, C.A., Halff, E.F., Koster, A.J., Huizinga, E.G., Koning, R.I.
Deposit date:2015-02-20
Release date:2015-11-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (40 Å)
Cite:Cryoelectron Tomography of the Naip5/Nlrc4 Inflammasome: Implications for Nlr Activation.
Structure, 23, 2015
5YUD
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FLAGELLIN DERIVATIVE IN COMPLEX WITH THE NLR PROTEIN NAIP5
Descriptor:Baculoviral IAP repeat-containing protein 1e, Phase 2 flagellin,Flagellin, ADENOSINE-5'-TRIPHOSPHATE
Authors:Yang, X.R., Yang, F., Wang, W.G., Lin, G.Z.
Deposit date:2017-11-21
Release date:2018-01-03
Last modified:2018-01-17
Method:ELECTRON MICROSCOPY (4.28 Å)
Cite:Structural basis for specific flagellin recognition by the NLR protein NAIP5.
Cell Res., 28, 2018
6B5B
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CRYO-EM STRUCTURE OF THE NAIP5-NLRC4-FLAGELLIN INFLAMMASOME
Descriptor:Baculoviral IAP repeat-containing protein 1e, NLR family CARD domain-containing protein 4, Flagellin
Authors:Tenthorey, J.L., Haloupek, N., Lopez-Blanco, J.R., Grob, P., Adamson, E., Hartenian, E., Lind, N.A., Bourgeois, N.M., Chacon, P., Nogales, E., Vance, R.E.
Deposit date:2017-09-29
Release date:2017-11-15
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Science, 358, 2017
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