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6HQA
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BU of 6hqa by Molmil
Molecular structure of promoter-bound yeast TFIID
Descriptor: Histone-fold, Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation, ...
Authors:Kolesnikova, O, Ben-Shem, A, Luo, J, Ranish, J, Schultz, P, Papai, G.
Deposit date:2018-09-24
Release date:2018-11-21
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Molecular structure of promoter-bound yeast TFIID.
Nat Commun, 9, 2018
6MZC
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BU of 6mzc by Molmil
Human TFIID BC core
Descriptor: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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BU of 6mzm by Molmil
Human TFIID bound to promoter DNA and TFIIA
Descriptor: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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BU of 6mzd by Molmil
Human TFIID Lobe A canonical
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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BU of 6mzl by Molmil
Human TFIID canonical state
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
7EDX
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BU of 7edx by Molmil
p53-bound TFIID-based core PIC on HDM2 promoter
Descriptor: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-17
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG9
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BU of 7eg9 by Molmil
TFIID-based intermediate PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG7
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BU of 7eg7 by Molmil
TFIID-based core PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGF
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BU of 7egf by Molmil
TFIID lobe A subcomplex
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 2021
7EG8
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BU of 7eg8 by Molmil
TFIID-based core PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGA
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BU of 7ega by Molmil
TFIID-based intermediate PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGG
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BU of 7egg by Molmil
TFIID lobe B subcomplex
Descriptor: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGB
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BU of 7egb by Molmil
TFIID-based holo PIC on SCP promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGI
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BU of 7egi by Molmil
TFIID in rearranged conformation
Descriptor: TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (9.82 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGD
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BU of 7egd by Molmil
SCP promoter-bound TFIID-TFIIA in initial TBP-loading state
Descriptor: DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (6.75 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGJ
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BU of 7egj by Molmil
SCP promoter-bound TFIID-TFIIA in post TBP-loading state
Descriptor: DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (8.64 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGE
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BU of 7ege by Molmil
TFIID in canonical conformation
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
8GXQ
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BU of 8gxq by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
Deposit date:2022-09-21
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (5.04 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXS
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BU of 8gxs by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
Deposit date:2022-09-21
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8WAL
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BU of 8wal by Molmil
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (8.52 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAK
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BU of 8wak by Molmil
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.47 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAS
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BU of 8was by Molmil
Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.13 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023

 

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