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7NA7
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BU of 7na7 by Molmil
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
Descriptor: Antibody fragment, CHOLESTEROL, Ghrelin-27, ...
Authors:Liu, H, Sun, D, Sun, J, Zhang, C.
Deposit date:2021-06-20
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
7W2Z
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BU of 7w2z by Molmil
Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex
Descriptor: Appetite-regulating hormone, CHOLESTEROL, Growth hormone secretagogue receptor type 1, ...
Authors:Qin, J, Ming, Q, Ji, S, Mao, C, Shen, D, Zhang, Y.
Deposit date:2021-11-24
Release date:2022-01-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular mechanism of agonism and inverse agonism in ghrelin receptor.
Nat Commun, 13, 2022
7F9Y
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BU of 7f9y by Molmil
ghrelin-bound ghrelin receptor in complex with Gq
Descriptor: CHOLESTEROL, Engineered G-alpha-q subunit, Ghrelin-28, ...
Authors:Wang, Y, Zhuang, Y, Xu, P, Xu, H.E, Jiang, Y.
Deposit date:2021-07-05
Release date:2021-08-18
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor.
Nat Commun, 12, 2021
8IBV
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BU of 8ibv by Molmil
Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ...
Authors:Jiang, Y, Xu, H.E, You, C, Xu, Y.
Deposit date:2023-02-10
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
1LBJ
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BU of 1lbj by Molmil
NMR solution structure of motilin in phospholipid bicellar solution
Descriptor: motilin
Authors:Andersson, A, Maler, L.
Deposit date:2002-04-03
Release date:2002-11-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR solution structure and dynamics of motilin in isotropic phospholipid bicellar solution
J.BIOMOL.NMR, 24, 2002
6H3E
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BU of 6h3e by Molmil
Receptor-bound Ghrelin conformation
Descriptor: Appetite-regulating hormone, octan-1-amine
Authors:Ferre, G, Damian, M, M'Kadmi, C, Saurel, O, Czaplicki, G, Demange, P, Marie, J, Fehrentz, J.A, Baneres, J.L, Milon, A.
Deposit date:2018-07-18
Release date:2019-07-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain.
Proc.Natl.Acad.Sci.USA, 116, 2019

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