1ECY
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PROTEASE INHIBITOR ECOTIN
Descriptor:ECOTIN, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE
Authors:Shin, D.H., Suh, S.W.
Deposit date:1996-08-06
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structure analyses of uncomplexed ecotin in two crystal forms: implications for its function and stability.
Protein Sci., 5, 1996
1ECZ
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PROTEASE INHIBITOR ECOTIN
Descriptor:ECOTIN, B-OCTYLGLUCOSIDE
Authors:Shin, D.H., Suh, S.W.
Deposit date:1996-08-06
Release date:1997-02-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Crystal structure analyses of uncomplexed ecotin in two crystal forms: implications for its function and stability.
Protein Sci., 5, 1996
1IFG
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CRYSTAL STRUCTURE OF A MONOMERIC FORM OF GENERAL PROTEASE INHIBITOR, ECOTIN IN ABSENCE OF A PROTEASE
Descriptor:ECOTIN
Authors:Eggers, C.T., Wang, S.X., Fletterick, R.J., Craik, C.S.
Deposit date:2001-04-12
Release date:2001-05-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of ecotin dimerization in protease inhibition.
J.Mol.Biol., 308, 2001
1N8O
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN BOVINE CHYMOTRYPSIN AND ECOTIN
Descriptor:Chymotrypsin A, A chain, b chain, ...
Authors:Cambillau, C., Spinelli, S., Lauwereys, M.
Deposit date:2002-11-21
Release date:2002-12-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Complex Between Bovine Chymotrypsin and Ecotin at 2.0 A Resolution
To be Published
1EZS
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CRYSTAL STRUCTURE OF ECOTIN MUTANT M84R, W67A, G68A, Y69A, D70A BOUND TO RAT ANIONIC TRYPSIN II
Descriptor:ECOTIN, TRYPSIN II, ANIONIC, ...
Authors:Gillmor, S.A., Takeuchi, T., Yang, S.Q., Craik, C.S., Fletterick, R.J.
Deposit date:2000-05-11
Release date:2000-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
1EZU
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ECOTIN Y69F, D70P BOUND TO D102N TRYPSIN
Descriptor:ECOTIN, TRYPSIN II, ANIONIC, ...
Authors:Gillmor, S.A., Takeuchi, T., Yang, S.Q., Craik, C.S., Fletterick, R.J.
Deposit date:2000-05-11
Release date:2000-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
1P0S
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CRYSTAL STRUCTURE OF BLOOD COAGULATION FACTOR XA IN COMPLEX WITH ECOTIN M84R
Descriptor:Coagulation factor X precursor, Ecotin precursor, MAGNESIUM ION, ...
Authors:Wang, S.X., Hur, E., Sousa, C.A., Brinen, L., Slivka, E.J., Fletterick, R.J.
Deposit date:2003-04-10
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Extended Interactions and Gla Domain of Blood Coagulation Factor Xa
Biochemistry, 42, 2003
1SLU
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN
Descriptor:ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S., Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
1SLV
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND
Descriptor:ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S., Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
1SLW
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; NICKEL-BOUND
Descriptor:ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S., Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
1SLX
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; ZINC-BOUND
Descriptor:ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S., Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
4IW4
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CRYSTAL STRUCTURE OF THE SERINE PROTEASE DOMAIN OF MASP-3 IN COMPLEX WITH ECOTIN
Descriptor:Ecotin, Mannan-binding lectin serine protease 3
Authors:Gaboriaud, C.
Deposit date:2013-01-23
Release date:2013-06-19
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Serine Protease Domain of MASP-3: Enzymatic Properties and Crystal Structure in Complex with Ecotin.
Plos One, 8, 2013
1AZZ
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FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN
Descriptor:COLLAGENASE, ECOTIN
Authors:Perona, J.J., Fletterick, R.J.
Deposit date:1997-11-24
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
Biochemistry, 36, 1997
1ID5
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CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEX WITH PROTEASE INHIBITOR ECOTIN
Descriptor:THROMBIN, ECOTIN, CALCIUM ION, ...
Authors:Wang, S.X., Fletterick, R.J.
Deposit date:2001-04-03
Release date:2001-09-05
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of thrombin-ecotin reveals conformational changes and extended interactions.
Biochemistry, 40, 2001
1XX9
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH ECOTINM84R
Descriptor:Coagulation factor XI, Ecotin, N-ACETYL-D-GLUCOSAMINE
Authors:Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
Deposit date:2004-11-04
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
1XXD
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN
Descriptor:Coagulation factor XI, Ecotin
Authors:Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
Deposit date:2004-11-04
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
1XXF
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH ECOTIN MUTANT (ECOTINP)
Descriptor:Coagulation factor XI, Ecotin, SODIUM ION
Authors:Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
Deposit date:2004-11-04
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
2Y6T
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MOLECULAR RECOGNITION OF CHYMOTRYPSIN BY THE SERINE PROTEASE INHIBITOR ECOTIN FROM YERSINIA PESTIS
Descriptor:CHYMOTRYPSINOGEN A, ECOTIN, SULFATE ION
Authors:Clark, E.A., Walker, N., Ford, D.C., Cooper, I.A., Oyston, P.C.F., Acharya, K.R.
Deposit date:2011-01-26
Release date:2011-04-20
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia Pestis.
J.Biol.Chem., 286, 2011
4NIY
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CRYSTAL STRUCTURE OF TRYPSILIGASE (K60E/N143H/Y151H/D189K TRYPSIN) COMPLEXED TO YRH-ECOTIN (M84Y/M85R/A86H ECOTIN)
Descriptor:Cationic trypsin, Ecotin, CALCIUM ION, ...
Authors:Schoepfel, M., Parthier, C., Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
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