5VCH
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CRYSTAL STRUCTURE OF FULL-LENGTH KLUYVEROMYCES LACTIS KAP123
Descriptor:Kap123
Authors:An, S., Yoon, J., Song, J.-J., Cho, U.-S.
Deposit date:2017-03-31
Release date:2017-11-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
5VE8
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CRYSTAL STRUCTURE OF FULL-LENGTH KLUYVEROMYCES LACTIS KAP123 WITH HISTONE H3 1-28
Descriptor:Kap123, Histone H3
Authors:An, S., Yoon, J., Song, J.-J., Cho, U.-S.
Deposit date:2017-04-04
Release date:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
5W0V
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CRYSTAL STRUCTURE OF FULL-LENGTH KLUYVEROMYCES LACTIS KAP123 WITH HISTONE H4 1-34
Descriptor:Kap123, Histone H4 1-34
Authors:An, S., Yoon, J., Song, J.-J., Cho, U.-S.
Deposit date:2017-05-31
Release date:2017-11-01
Method:X-RAY DIFFRACTION (2.821 Å)
Cite:Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
1GCJ
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N-TERMINAL FRAGMENT OF IMPORTIN-BETA
Descriptor:IMPORTIN BETA
Authors:Lee, S.J., Imamoto, N., Sakai, H., Nakagawa, A., Kose, S., Koike, M., Yamamoto, M., Kumasaka, T., Yoneda, Y., Tsukihara, T.
Deposit date:2000-07-31
Release date:2000-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport.
J.Mol.Biol., 302, 2000
1QBK
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STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX
Descriptor:KARYOPHERIN BETA2, RAN, MAGNESIUM ION, ...
Authors:Chook, Y.M., Blobel, G.
Deposit date:1999-04-23
Release date:1999-06-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.
Nature, 399, 1999
1UKL
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CRYSTAL STRUCTURE OF IMPORTIN-BETA AND SREBP-2 COMPLEX
Descriptor:Importin beta-1 subunit, Sterol regulatory element binding protein-2
Authors:Lee, S.J., Sekimoto, T., Yamashita, E., Nagoshi, E., Nakagawa, A., Imamoto, N., Yoshimura, M., Sakai, H., Tsukihara, T., Yoneda, Y.
Deposit date:2003-08-26
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor
Science, 302, 2003
2H4M
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KARYOPHERIN BETA2/TRANSPORTIN-M9NLS
Descriptor:Transportin-1, Heterogeneous nuclear ribonucleoprotein A1
Authors:Chook, Y.M., Cansizoglu, A.E.
Deposit date:2006-05-24
Release date:2006-10-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
2OT8
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KARYOPHERIN BETA2/TRANSPORTIN-HNRNPM NLS COMPLEX
Descriptor:Transportin-1, Heterogeneous nuclear ribonucleoprotein M
Authors:Cansizoglu, A.E., Chook, Y.M.
Deposit date:2007-02-07
Release date:2007-04-10
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a pathway-specific nuclear import inhibitor.
Nat.Struct.Mol.Biol., 14, 2007
2QMR
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KARYOPHERIN BETA2/TRANSPORTIN
Descriptor:Transportin-1
Authors:Cansizoglu, A.E., Chook, Y.M.
Deposit date:2007-07-16
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational heterogeneity of karyopherin beta2 is segmental
Structure, 15, 2007
2Z5J
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FREE TRANSPORTIN 1
Descriptor:Transportin-1
Authors:Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Yamada, M., Sato, M.
Deposit date:2007-07-13
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5K
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COMPLEX OF TRANSPORTIN 1 WITH TAP NLS
Descriptor:Transportin-1, Nuclear RNA export factor 1, PHOSPHATE ION
Authors:Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Yamada, M., Kose, S., Imamoto, N., Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5M
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COMPLEX OF TRANSPORTIN 1 WITH TAP NLS, CRYSTAL FORM 2
Descriptor:Transportin-1, Nuclear RNA export factor 1
Authors:Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Kose, S., Imamoto, N., Yamada, M., Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5N
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COMPLEX OF TRANSPORTIN 1 WITH HNRNP D NLS
Descriptor:Transportin-1, Heterogeneous nuclear ribonucleoprotein D0
Authors:Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Kose, S., Imamoto, N., Yamada, M., Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5O
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COMPLEX OF TRANSPORTIN 1 WITH JKTBP NLS
Descriptor:Transportin-1, Heterogeneous nuclear ribonucleoprotein D-like
Authors:Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Kose, S., Imamoto, N., Yamada, M., Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
3GB8
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CRYSTAL STRUCTURE OF CRM1/SNURPORTIN-1 COMPLEX
Descriptor:Exportin-1, Snurportin-1
Authors:Dong, X., Biswas, A., Suel, K.E., Jackson, L.K., Martinez, R., Gu, H., Chook, Y.M.
Deposit date:2009-02-19
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for leucine-rich nuclear export signal recognition by CRM1.
Nature, 458, 2009
3GJX
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CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT COMPLEX CRM1-SNURPORTIN1-RANGTP
Descriptor:Snurportin-1, GTP-binding nuclear protein Ran, Exportin-1, ...
Authors:Monecke, T., Guettler, T., Neumann, P., Dickmanns, A., Goerlich, D., Ficner, R.
Deposit date:2009-03-09
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Science, 2009
3NBY
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CRYSTAL STRUCTURE OF THE PKI NES-CRM1-RANGTP NUCLEAR EXPORT COMPLEX
Descriptor:Snurportin-1, GTP-binding nuclear protein Ran, Exportin-1, ...
Authors:Guttler, T., Madl, T., Neumann, P., Deichsel, D., Corsini, L., Monecke, T., Ficner, R., Sattler, M., Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBZ
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CRYSTAL STRUCTURE OF THE HIV-1 REV NES-CRM1-RANGTP NUCLEAR EXPORT COMPLEX (CRYSTAL I)
Descriptor:Exportin-1, Snurportin-1, GTP-binding nuclear protein Ran, ...
Authors:Guttler, T., Madl, T., Neumann, P., Deichsel, D., Corsini, L., Monecke, T., Ficner, R., Sattler, M., Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC0
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CRYSTAL STRUCTURE OF THE HIV-1 REV NES-CRM1-RANGTP NUCLEAR EXPORT COMPLEX (CRYSTAL II)
Descriptor:Exportin-1, Snurportin-1, GTP-binding nuclear protein Ran, ...
Authors:Guttler, T., Madl, T., Neumann, P., Deichsel, D., Corsini, L., Monecke, T., Ficner, R., Sattler, M., Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC1
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CRYSTAL STRUCTURE OF THE CRM1-RANGTP COMPLEX
Descriptor:GTP-binding nuclear protein Ran, Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T., Madl, T., Neumann, P., Deichsel, D., Corsini, L., Monecke, T., Ficner, R., Sattler, M., Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3VYC
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CRYSTAL STRUCTURE OF UNLIGANDED SACCHAROMYCES CEREVISIAE CRM1 (XPO1P)
Descriptor:Exportin-1
Authors:Saito, N., Matsuura, Y.
Deposit date:2012-09-22
Release date:2012-11-28
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A 2.1- angstrom -resolution crystal structure of unliganded CRM1 reveals the mechanism of autoinhibition
J.Mol.Biol., 425, 2013
3ZKV
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IMPORTIN13 CYTOSOLIC STATE
Descriptor:CADMUS
Authors:Gruenwald, M., Lazzaretti, D., Bono, F.
Deposit date:2013-01-24
Release date:2013-04-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
4BSM
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CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 (EXPORTIN-1) LACKING THE C-TERMINAL HELICAL EXTENSION AT 4.5A
Descriptor:EXPORTIN-1
Authors:Dian, C., Bernaudat, F., Langer, K., Oliva, M.F., Fornerod, M., Schoehn, G., Muller, C.W., Petosa, C.
Deposit date:2013-06-10
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4BSN
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CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 (EXPORTIN-1) LACKING THE C-TERMINAL HELICAL EXTENSION AT 4.1A
Descriptor:EXPORTIN-1
Authors:Dian, C., Bernaudat, F., Langer, K., Oliva, M.F., Fornerod, M., Schoehn, G., Muller, C.W., Petosa, C.
Deposit date:2013-06-11
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4FDD
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CRYSTAL STRUCTURE OF KAP BETA2-PY-NLS
Descriptor:Transportin-1, RNA-binding protein FUS
Authors:Zhang, Z.C., Chook, Y.M.
Deposit date:2012-05-28
Release date:2012-07-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
Proc.Natl.Acad.Sci.USA, 109, 2012
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