3TEW
 
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4H2A
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3MHZ
 | | 1.7A structure of 2-fluorohistidine labeled Protective Antigen | | Descriptor: | CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL | | Authors: | Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. | | Deposit date: | 2010-04-09 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation.
Biochemistry, 49, 2010
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3TEX
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4NAM
 | | 1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y) | | Descriptor: | CALCIUM ION, Protective antigen | | Authors: | Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G. | | Deposit date: | 2013-10-22 | | Release date: | 2014-01-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | (19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability.
Biochemistry, 53, 2014
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3TEZ
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4EE2
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5FR3
 | | X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E) | | Descriptor: | CALCIUM ION, GLYCEROL, PROTECTIVE ANTIGEN | | Authors: | Ganesan, A, Siekierska, A, Beerten, J, Brams, M, van Durme, J, De Baets, G, van der Kant, R, Gallardo, R, Ramakers, M, Langenberg, T, Wilkinson, H, De Smet, F, Ulens, C, Rousseau, F, Schymkowitz, J. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.935 Å) | | Cite: | Structural Hot Spots for the Solubility of Globular Proteins
Nat.Commun., 7, 2016
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3Q8B
 | | Crystal structure of WT Protective Antigen (pH 9.0) | | Descriptor: | CALCIUM ION, Protective antigen | | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | | Deposit date: | 2011-01-06 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
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3Q8E
 | | Crystal structure of Protective Antigen W346F (pH 8.5) | | Descriptor: | CALCIUM ION, Protective antigen | | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | | Deposit date: | 2011-01-06 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
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1ACC
 | | ANTHRAX PROTECTIVE ANTIGEN | | Descriptor: | ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION | | Authors: | Petosa, C, Liddington, R.C. | | Deposit date: | 1997-02-05 | | Release date: | 1998-02-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
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3Q8F
 | | Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) | | Descriptor: | CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL | | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | | Deposit date: | 2011-01-06 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
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3TEY
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1T6B
 | | Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor | | Descriptor: | Anthrax toxin receptor 2, CALCIUM ION, MANGANESE (II) ION, ... | | Authors: | Santelli, E, Bankston, L.A, Leppla, S.H, Liddington, R.C. | | Deposit date: | 2004-05-05 | | Release date: | 2004-07-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a complex between anthrax toxin and its host cell receptor
Nature, 430, 2004
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8DCM
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7VNJ
 | | Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with short stem | | Descriptor: | ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosyltransferase enzymatic component, CALCIUM ION | | Authors: | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | | Deposit date: | 2021-10-11 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
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7VNN
 | | Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with long stem | | Descriptor: | ADP-ribosylating binary toxin binding subunit CdtB, CALCIUM ION, CdtA | | Authors: | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | | Deposit date: | 2021-10-11 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-02 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
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6UWR
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7YVS
 | | Complex structure of Clostridioides difficile binary toxin unfolded CDTa-bound CDTb-pore (short). | | Descriptor: | ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION | | Authors: | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | | Deposit date: | 2022-08-19 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-02 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
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6KLO
 | | Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem | | Descriptor: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | | Deposit date: | 2019-07-30 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
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3Q8C
 | | Crystal structure of Protective Antigen W346F (pH 5.5) | | Descriptor: | CALCIUM ION, Protective antigen | | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | | Deposit date: | 2011-01-06 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
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6KLW
 | | Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem | | Descriptor: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | | Deposit date: | 2019-07-30 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
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6KLX
 | | Pore structure of Iota toxin binding component (Ib) | | Descriptor: | CALCIUM ION, Iota toxin component Ib | | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | | Deposit date: | 2019-07-30 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
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3J9C
 | | CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution | | Descriptor: | CALCIUM ION, Protective antigen PA-63 | | Authors: | Jiang, J, Pentelute, B.L, Collier, R.J, Zhou, Z.H. | | Deposit date: | 2014-12-25 | | Release date: | 2015-03-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Atomic structure of anthrax protective antigen pore elucidates toxin translocation.
Nature, 521, 2015
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6UWT
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