PDB: 69 resultsInfo pagesStatus searchChemie searchBIRD

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1R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN Authors: Eriksson, M, Eklund, H. Deposit date: 1997-07-15 Release date: 1998-01-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
1RLR	STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1 Descriptor: RIBONUCLEOTIDE REDUCTASE PROTEIN R1 Authors: Uhlin, U, Eklund, H. Deposit date: 1994-08-12 Release date: 1996-12-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of ribonucleotide reductase protein R1. Nature, 370, 1994
1ZYZ	Structures of Yeast Ribonucloetide Reductase I Descriptor: GLYCINE, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-13 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZZD	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-13 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVU	Structures of Yeast Ribonucleotide Reductase I Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW	Structures of Yeast Ribonucleotide Reductase I Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVX	Structures of Yeast Ribonucleotide Reductase I Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY	Structures of Yeast Ribonucleotide Reductase I Descriptor: 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2EUD	Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides Descriptor: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J. Deposit date: 2005-10-28 Release date: 2006-03-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
2R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE Authors: Eriksson, M, Eklund, H. Deposit date: 1997-07-21 Release date: 1998-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
2X0X	Ribonucleotide reductase R1 subunit of E. coli to 2.3 A resolution Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA, SULFATE ION Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2009-12-18 Release date: 2010-01-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAK	Ribonucleotide reductase Y730NO2Y modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAP	Ribonucleotide reductase Y731NO2Y modified R1 subunit of E. coli to 2. 1 A resolution Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAV	Ribonucleotide reductase Y731NO2Y and Y730F modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAW	Ribonucleotide reductase Y730NO2Y and Y731F modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAX	Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAY	Ribonucleotide reductase Y730NO2Y and C439A modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAZ	Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XO4	RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases. J.Am.Chem.Soc., 133, 2011
2XO5	RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases. J.Am.Chem.Soc., 133, 2011
2ZLF	The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase Descriptor: FTLDADF, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. Deposit date: 2008-04-09 Release date: 2008-08-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.59 Å) Cite: The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
2ZLG	The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase Descriptor: (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. Deposit date: 2008-04-09 Release date: 2008-08-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.52 Å) Cite: The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008

 

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