PDB: 74 resultsInfo pagesStatus searchChemie searchBIRD

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2L7E	The structure of a domain from yeast Descriptor: Transcription initiation factor TFIID subunit 14 Authors: Zhang, W, Zhang, J, Tu, X. Deposit date: 2010-12-08 Release date: 2011-03-23 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: solution structure of Taf14 YEATS domain To be Published
2NDF	Solution NMR structures of AF9 yeats domain in complex with histon H3 acetylation at K18 Descriptor: Histone H3 peptide, Protein AF-9 Authors: Zeng, L, Zhou, M. Deposit date: 2016-05-19 Release date: 2016-09-07 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain. Structure, 24, 2016
2NDG	Solution NMR structures of AF9 yeats domain in complex with histone H3 crotonylation at K18 Descriptor: Histone H3 peptide, Protein AF-9 Authors: Zeng, L, Zhou, M. Deposit date: 2016-05-19 Release date: 2016-09-07 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain. Structure, 24, 2016
3FK3	Structure of the Yeats Domain, Yaf9 Descriptor: Protein AF-9 homolog Authors: Wang, A.Y, Schulze, J.M, Skordalakes, E, Berger, J.M, Rine, J, Kobor, M.S. Deposit date: 2008-12-15 Release date: 2009-10-27 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation Proc.Natl.Acad.Sci.USA, 106, 2009
3QRL	Crystal Structure of the Taf14 YEATS domain Descriptor: TRIETHYLENE GLYCOL, Transcription initiation factor TFIID subunit 14 Authors: Simpson, P.J, Warren, A.J. Deposit date: 2011-02-18 Release date: 2012-02-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the Taf14 YEATS domain To be Published
3RLS	Crystal structure of yeast AF-9 homolog protein Yaf9 Descriptor: Protein AF-9 homolog Authors: Chen, S.D, Wu, L.J, Liu, Y.F. Deposit date: 2011-04-20 Release date: 2011-05-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of yeast AF-9 homolog protein yaf9 To be Published
4TMP	Crystal structure of AF9 YEATS bound to H3K9ac peptide Descriptor: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9 Authors: Li, H, Li, Y, Wang, H, Ren, Y. Deposit date: 2014-06-02 Release date: 2014-11-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation. Cell, 159, 2014
5D7E	Crystal structure of Taf14 YEATS domain in complex with H3K9ac Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, H3K9ac, ... Authors: Andrews, F.H, Shanle, E.K, Strahl, B.D, Kutateladze, T.G. Deposit date: 2015-08-13 Release date: 2015-09-23 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response. Genes Dev., 29, 2015
5HJB	AF9 YEATS in complex with histone H3 Crotonylation at K9 Descriptor: Protein AF-9, peptide of Histone H3.1 Authors: Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. Deposit date: 2016-01-12 Release date: 2016-04-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
5HJD	AF9 YEATS in complex with histone H3 Crotonylation at K18 Descriptor: COPPER (II) ION, Protein AF-9, SULFATE ION, ... Authors: Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. Deposit date: 2016-01-13 Release date: 2016-04-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.806 Å) Cite: Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Mol.Cell, 62, 2016
5IOK	Crystal structure of Taf14 YEATS domain in complex with histone H3K9cr Descriptor: (ACE)QTAR(KCR)ST, DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14 Authors: Andrews, F.H, Kuateladze, T.G. Deposit date: 2016-03-08 Release date: 2016-04-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.22 Å) Cite: The Taf14 YEATS domain is a reader of histone crotonylation. Nat.Chem.Biol., 12, 2016
5IQL	Crystal structure of YEATS2 YEATS bound to H3K27cr peptide Descriptor: Histone H3.1, YEATS domain-containing protein 2 Authors: Li, H, Zhao, D, Guan, H. Deposit date: 2016-03-11 Release date: 2016-07-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: YEATS2 is a selective histone crotonylation reader. Cell Res., 26, 2016
5J9S	ENL YEATS in complex with histone H3 acetylation at K27 Descriptor: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION Authors: Li, Y, Li, H. Deposit date: 2016-04-11 Release date: 2017-03-08 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.702 Å) Cite: ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia Nature, 543, 2017
5R68	XChem group deposition -- Crystal Structure of human YEATS4 in complex with FM000199e Descriptor: (1-methylbenzotriazol-5-yl)methanol, 1,2-ETHANEDIOL, YEATS domain-containing protein 4 Authors: Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M. Deposit date: 2020-02-29 Release date: 2020-12-30 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.64 Å) Cite: XChem group deposition To Be Published
5R69	XChem group deposition -- Crystal Structure of human YEATS4 in complex with XS038644e Descriptor: 1,2-ETHANEDIOL, YEATS domain-containing protein 4, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide Authors: Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M. Deposit date: 2020-02-29 Release date: 2020-12-30 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.83 Å) Cite: XChem group deposition To Be Published
5SVA	Mediator-RNA Polymerase II Pre-Initiation Complex Descriptor: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... Authors: Robinson, P.J, Bushnell, D.A, Kornberg, R.D. Deposit date: 2016-08-05 Release date: 2016-09-28 Last modified: 2019-11-27 Method: ELECTRON MICROSCOPY (15.3 Å) Cite: Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell, 166, 2016
5VNA	Crystal structure of human YEATS domain Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ... Authors: Cho, H.J, Cierpicki, T. Deposit date: 2017-04-29 Release date: 2018-09-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode. ACS Chem. Biol., 13, 2018
5VNB	YEATS in complex with histone H3 Descriptor: 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ... Authors: Cho, H.J, Cierpicki, T. Deposit date: 2017-04-29 Release date: 2018-09-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode. ACS Chem. Biol., 13, 2018
5WYI	The Yaf9 YEATS domain Recognizing H3K122suc Peptide Descriptor: (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid, ILE-MET-PRO-LYS-ASP-ILE-GLN-LEU, SUCCINIC ACID, ... Authors: Wang, Y, Hao, Q. Deposit date: 2017-01-13 Release date: 2018-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: The Yaf9 YEATS domain Recognizing H3K122suc Peptide To Be Published
5XNV	Crystal structure of YEATS2 YEATS bound to H3K27ac peptide Descriptor: ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... Authors: Li, H.T, Guan, H.P, Zhao, D. Deposit date: 2017-05-24 Release date: 2017-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.696 Å) Cite: YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nat Commun, 8, 2017
5XTZ	Crystal structure of GAS41 YEATS bound to H3K27ac peptide Descriptor: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4 Authors: Li, H.T, Zhao, D. Deposit date: 2017-06-21 Release date: 2018-06-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.105 Å) Cite: Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity. Cell Discov, 4, 2018
5Y8V	Crystal structure of GAS41 Descriptor: MAGNESIUM ION, YEATS domain-containing protein 4 Authors: Wang, Y, Hao, Q. Deposit date: 2017-08-21 Release date: 2018-04-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YYF	Crystal structure of AF9 YEATS domain in complex with a peptide inhibitor "PHQ-H3(Q5-K9)" modified at K9 with 2-furancarboyl group Descriptor: 2-FUROIC ACID, Peptide inhibitor PHQ-H3(Q5-K9), Protein AF-9, ... Authors: Li, Y, Li, H. Deposit date: 2017-12-09 Release date: 2018-11-07 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.903 Å) Cite: Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking. Nat. Chem. Biol., 14, 2018
6AXJ	Crystal structure of the Yaf9 YEATS domain bound to H3K27ac Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ... Authors: Klein, B.J, Kutateladze, T.G. Deposit date: 2017-09-06 Release date: 2017-11-22 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (2.379 Å) Cite: Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain. Nucleic Acids Res., 46, 2018
6HPW	Crystal structure of ENL (MLLT1) in complex with compound 20 Descriptor: 1,2-ETHANEDIOL, 3-iodanyl-4-methyl-~{N}-[2-(piperidin-1-ylmethyl)-3~{H}-benzimidazol-5-yl]benzamide, Protein ENL Authors: Heidenreich, D, Chaikuad, A, Moustakim, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brennan, P.E, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2018-09-22 Release date: 2018-11-28 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL). J.Med.Chem., 61, 2018

 

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