2L7E
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THE STRUCTURE OF A DOMAIN FROM YEAST
Descriptor:Transcription initiation factor TFIID subunit 14
Authors:Zhang, W., Zhang, J., Tu, X.
Deposit date:2010-12-08
Release date:2011-03-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:solution structure of Taf14 YEATS domain
To be Published
2NDF
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SOLUTION NMR STRUCTURES OF AF9 YEATS DOMAIN IN COMPLEX WITH HISTON H3 ACETYLATION AT K18
Descriptor:Protein AF-9, Histone H3 peptide
Authors:Zeng, L., Zhou, M.
Deposit date:2016-05-19
Release date:2016-09-07
Last modified:2016-09-21
Method:SOLUTION NMR
Cite:Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
2NDG
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SOLUTION NMR STRUCTURES OF AF9 YEATS DOMAIN IN COMPLEX WITH HISTONE H3 CROTONYLATION AT K18
Descriptor:Protein AF-9, Histone H3 peptide
Authors:Zeng, L., Zhou, M.
Deposit date:2016-05-19
Release date:2016-09-07
Last modified:2016-09-21
Method:SOLUTION NMR
Cite:Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
3FK3
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STRUCTURE OF THE YEATS DOMAIN, YAF9
Descriptor:Protein AF-9 homolog
Authors:Wang, A.Y., Schulze, J.M., Skordalakes, E., Berger, J.M., Rine, J., Kobor, M.S.
Deposit date:2008-12-15
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation
Proc.Natl.Acad.Sci.USA, 106, 2009
3QRL
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CRYSTAL STRUCTURE OF THE TAF14 YEATS DOMAIN
Descriptor:Transcription initiation factor TFIID subunit 14, TRIETHYLENE GLYCOL
Authors:Simpson, P.J., Warren, A.J.
Deposit date:2011-02-18
Release date:2012-02-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Taf14 YEATS domain
To be Published
3RLS
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CRYSTAL STRUCTURE OF YEAST AF-9 HOMOLOG PROTEIN YAF9
Descriptor:Protein AF-9 homolog
Authors:Chen, S.D., Wu, L.J., Liu, Y.F.
Deposit date:2011-04-20
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of yeast AF-9 homolog protein yaf9
To be Published
4TMP
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CRYSTAL STRUCTURE OF AF9 YEATS BOUND TO H3K9AC PEPTIDE
Descriptor:Protein AF-9, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, 1,2-ETHANEDIOL
Authors:Li, H., Li, Y., Wang, H., Ren, Y.
Deposit date:2014-06-02
Release date:2014-11-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
5D7E
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN IN COMPLEX WITH H3K9AC
Descriptor:Transcription initiation factor TFIID subunit 14, H3K9ac, DI(HYDROXYETHYL)ETHER, ...
Authors:Andrews, F.H., Shanle, E.K., Strahl, B.D., Kutateladze, T.G.
Deposit date:2015-08-13
Release date:2015-09-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev., 29, 2015
5HJB
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AF9 YEATS IN COMPLEX WITH HISTONE H3 CROTONYLATION AT K9
Descriptor:Protein AF-9, peptide of Histone H3.1
Authors:Li, Y.Y., Zhao, D., Guan, H.P., Li, H.T.
Deposit date:2016-01-12
Release date:2016-04-20
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
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AF9 YEATS IN COMPLEX WITH HISTONE H3 CROTONYLATION AT K18
Descriptor:Protein AF-9, peptide of Histone H3.1, COPPER (II) ION, ...
Authors:Li, Y.Y., Zhao, D., Guan, H.P., Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
5IOK
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN IN COMPLEX WITH HISTONE H3K9CR
Descriptor:Transcription initiation factor TFIID subunit 14, (ACE)QTAR(KCR)ST, DI(HYDROXYETHYL)ETHER
Authors:Andrews, F.H., Kuateladze, T.G.
Deposit date:2016-03-08
Release date:2016-04-20
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The Taf14 YEATS domain is a reader of histone crotonylation.
Nat.Chem.Biol., 12, 2016
5IQL
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CRYSTAL STRUCTURE OF YEATS2 YEATS BOUND TO H3K27CR PEPTIDE
Descriptor:YEATS domain-containing protein 2, Histone H3.1
Authors:Li, H., Zhao, D., Guan, H.
Deposit date:2016-03-11
Release date:2016-07-20
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:YEATS2 is a selective histone crotonylation reader.
Cell Res., 26, 2016
5J9S
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ENL YEATS IN COMPLEX WITH HISTONE H3 ACETYLATION AT K27
Descriptor:Protein ENL, H3K27ac peptide from Histone H3.1, SULFATE ION
Authors:Li, Y., Li, H.
Deposit date:2016-04-11
Release date:2017-03-08
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
Nature, 543, 2017
5VNA
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CRYSTAL STRUCTURE OF HUMAN YEATS DOMAIN
Descriptor:YEATS domain-containing protein 4, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Cho, H.J., Cierpicki, T.
Deposit date:2017-04-29
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
5VNB
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YEATS IN COMPLEX WITH HISTONE H3
Descriptor:YEATS domain-containing protein 4, H3K23acK27ac peptide, 1,2-ETHANEDIOL, ...
Authors:Cho, H.J., Cierpicki, T.
Deposit date:2017-04-29
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
5WYI
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THE YAF9 YEATS DOMAIN RECOGNIZING H3K122SUC PEPTIDE
Descriptor:Yaf9, ILE-MET-PRO-LYS-ASP-ILE-GLN-LEU, (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid, ...
Authors:Wang, Y., Hao, Q.
Deposit date:2017-01-13
Release date:2018-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Yaf9 YEATS domain Recognizing H3K122suc Peptide
To Be Published
5XNV
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CRYSTAL STRUCTURE OF YEATS2 YEATS BOUND TO H3K27AC PEPTIDE
Descriptor:YEATS domain-containing protein 2, ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, ...
Authors:Li, H.T., Guan, H.P., Zhao, D.
Deposit date:2017-05-24
Release date:2017-11-01
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
5XTZ
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CRYSTAL STRUCTURE OF GAS41 YEATS BOUND TO H3K27AC PEPTIDE
Descriptor:YEATS domain-containing protein 4, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, ACETATE ION
Authors:Li, H.T., Zhao, D.
Deposit date:2017-06-21
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
5Y8V
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CRYSTAL STRUCTURE OF GAS41
Descriptor:YEATS domain-containing protein 4, MAGNESIUM ION
Authors:Wang, Y., Hao, Q.
Deposit date:2017-08-21
Release date:2018-04-25
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YYF
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CRYSTAL STRUCUTRE OF AF9 YEATS DOMAIN IN COMPLEX WITH A PEPTIDE INHIBITOR "PHQ-H3(Q5-K9)" MODIFIED AT K9 WITH 2-FURANCARBOYL GROUP
Descriptor:Protein AF-9, Peptide inhibitor PHQ-H3(Q5-K9), SULFATE ION, ...
Authors:Li, Y., Li, H.
Deposit date:2017-12-09
Release date:2018-11-07
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking
Nat.Chem.Biol., 2018
6AXJ
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CRYSTAL STRUCTURE OF THE YAF9 YEATS DOMAIN BOUND TO H3K27AC
Descriptor:Protein AF-9 homolog, ALY-SER-ALA-PRO-ALA, SULFATE ION, ...
Authors:Klein, B.J., Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
6HT0
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CRYSTAL STRUCTURE OF MLLT1 (ENL) YEATS DOMAIN IN COMPLEXED WITH COMPOUND 94
Descriptor:Protein ENL, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Heidenreich, D., Chaikuad, A., Moustakim, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Fedorov, O., Brennan, P.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2018-10-02
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of an MLLT1/3 YEATS Domain Chemical Probe.
Angew. Chem. Int. Ed. Engl., 2018
6HT1
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CRYSTAL STRUCTURE OF MLLT1 (ENL) YEATS DOMAIN IN COMPLEXED WITH SGC-IMLLT (COMPOUND 92)
Descriptor:Protein ENL, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Heidenreich, D., Chaikuad, A., Moustakim, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Fedorov, O., Brennan, P.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2018-10-02
Release date:2018-10-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of an MLLT1/3 YEATS Domain Chemical Probe.
Angew. Chem. Int. Ed. Engl., 2018
5SVA
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MEDIATOR-RNA POLYMERASE II PRE-INITIATION COMPLEX
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Robinson, P.J., Bushnell, D.A., Kornberg, R.D.
Deposit date:2016-08-05
Release date:2016-09-28
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
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