6FXK
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXM
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH MN2+
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXR
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXT
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GLC
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXX
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL, HG2+ SOAK
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, MERCURY (II) ION, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXY
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL - STRUCTURE FROM LONG-WAVELENGTH S-SAD
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.138 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
1BK0
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, SULFATE ION, FE (III) ION, ...
Authors:Roach, P.L., Clifton, I.J., Hensgens, C.M.H., Shibata, N., Schofield, C.J., Hajdu, J., Baldwin, J.E.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
Nature, 387, 1997
1BLZ
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE-NO COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, FE (III) ION, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:Roach, P.L., Clifton, I.J., Hensgens, C.M.H., Shibata, N., Schofield, C.J., Hajdu, J., Baldwin, J.E.
Deposit date:1998-07-22
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
Nature, 387, 1997
1DCS
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DEACETOXYCEPHALOSPORIN C SYNTHASE FROM S. CLAVULIGERUS
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, SULFATE ION
Authors:Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Schofield, C.J., Hajdu, J., Andersson, I.
Deposit date:1998-06-05
Release date:1999-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of a cephalosporin synthase.
Nature, 394, 1998
1E5H
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DELTA-R307A DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH SUCCINATE AND CARBON DIOXIDE
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, SUCCINIC ACID, ...
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1E5I
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DELTA-R306 DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH IRON AND 2-OXOGLUTARATE.
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXOGLUTARIC ACID
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1GP4
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ANTHOCYANIDIN SYNTHASE FROM ARABIDOPSIS THALIANA (SELENOMETHIONINE SUBSTITUTED)
Descriptor:ANTHOCYANIDIN SYNTHASE, 2-OXOGLUTARIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Wilmouth, R.C., Turnbull, J.J., Welford, R.W.D., Clifton, I.J., Prescott, A.G., Schofield, C.J.
Deposit date:2001-10-30
Release date:2002-02-21
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis Thaliana.
Structure, 10, 2002
1GP5
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ANTHOCYANIDIN SYNTHASE FROM ARABIDOPSIS THALIANA COMPLEXED WITH TRANS-DIHYDROQUERCETIN
Descriptor:LEUCOANTHOCYANIDIN DIOXYGENASE, 2-OXOGLUTARIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Wilmouth, R.C., Turnbull, J.J., Welford, R.W.D., Clifton, I.J., Prescott, A.G., Schofield, C.J.
Deposit date:2001-10-30
Release date:2002-02-21
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis Thaliana.
Structure, 10, 2002
1GP6
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ANTHOCYANIDIN SYNTHASE FROM ARABIDOPSIS THALIANA COMPLEXED WITH TRANS-DIHYDROQUERCETIN (WITH 30 MIN EXPOSURE TO O2)
Descriptor:LEUCOANTHOCYANIDIN DIOXYGENASE, SUCCINIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Wilmouth, R.C., Turnbull, J.J., Welford, R.W.D., Clifton, I.J., Prescott, A.G., Schofield, C.J.
Deposit date:2001-10-30
Release date:2002-02-21
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis Thaliana.
Structure, 10, 2002
1HB1
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1R)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOMETHYL)-2-OXOETHYL]-6-OXO-D-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB2
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB3
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB4
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HJF
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXO-4-METHYLPENTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1HJG
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 3-METHYL-2-OXOBUTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1IPS
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, MANGANESE (II) ION
Authors:Roach, P.L., Clifton, I.J., Fulop, V., Harlos, K., Barton, G.J., Hajdu, J., Andersson, I., Schofield, C.J., Baldwin, J.E.
Deposit date:1997-03-21
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
Nature, 375, 1995
1OBN
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ISOPENICILLIN N SYNTHASE AMINOADIPOYL-CYSTEINYL-AMINOBUTYRATE-FE-NO COMPLEX
Descriptor:ISOPENICILLIN N SYNTHETASE, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, FE (II) ION, ...
Authors:Long, A.J., Clifton, I.J., Roach, P.L., Baldwin, J.E., Schofield, C.J., Rutledge, P.J.
Deposit date:2003-01-31
Release date:2004-02-02
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Studies on the Reaction of Isopenicillin N Synthase with the Substrate Analogue Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D-Alpha-Aminobutyrate.
Biochem.J., 372, 2003
1OC1
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ISOPENICILLIN N SYNTHASE AMINOADIPOYL-CYSTEINYL-AMINOBUTYRATE-FE COMPLEX
Descriptor:ISOPENICILLIN N SYNTHETASE, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, FE (II) ION, ...
Authors:Long, A.J., Clifton, I.J., Roach, P.L., Baldwin, J.E., Schofield, C.J., Rutledge, P.J.
Deposit date:2003-02-03
Release date:2004-02-02
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Studies on the Reaction of Isopenicillin N Synthase with the Substrate Analogue Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D-Alpha-Aminobutyrate
Biochem.J., 372, 2003
1ODM
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, SULFATE ION, ...
Authors:Elkins, J.M., Rutledge, P.J., Burzlaff, N.I., Clifton, I.J., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2003-02-19
Release date:2003-06-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystallographic Studies on the Reaction of Isopenicillin N Synthase with an Unsaturated Substrate Analogue
Org.Biomol.Chem., 1, 2003
1ODN
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN-EXPOSED PRODUCT FROM ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, 6-(5-AMINO-5-CARBOXY-PENTANOYLAMINO)-3-HYDROXYMETHYL-7-OXO-4-THIA-1-AZA-BICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, SULFATE ION, ...
Authors:Elkins, J.M., Rutledge, P.J., Burzlaff, N.I., Clifton, I.J., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2003-02-19
Release date:2003-06-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Studies on the Reaction of Isopenicillin N Synthase with an Unsaturated Substrate Analogue
Org.Biomol.Chem., 1, 2003
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