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6X1J
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BU of 6x1j by Molmil
The homing endonuclease I-WcaI bound to its DNA recognition sequence
Descriptor: DNA (25-mer), POTASSIUM ION, Probable intron-encoded endonuclease 1
Authors:Nawimanage, R, Lohman, J.R, Gimble, F.S.
Deposit date:2020-05-19
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.945 Å)
Cite:Structure-Function Studies of Two Yeast Homing Endonucleases that Evolved to Cleave Identical Targets with Dissimilar Rates and Specificities.
J.Mol.Biol., 434, 2022
5A0M
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BU of 5a0m by Molmil
THE CRYSTAL STRUCTURE OF I-SCEI IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF MN
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP)-3', 5'-D(*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*CP)-3', 5'-D(*CP*CP*CP*TP*AP*GP*CP*GP*TP)-3', ...
Authors:Prieto, J, Redondo, P, Merino, N, Villate, M, Blanco, F.J, Molina, R.
Deposit date:2015-04-21
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the I-Scei Nuclease Complexed with its DsDNA Target and Three Catalytic Metal Ions.
Acta Crystallogr.,Sect.F, 72, 2016
3OOR
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BU of 3oor by Molmil
I-SceI mutant (K86R/G100T)complexed with C/G+4 DNA substrate
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ...
Authors:Joshi, R, Chen, J.-H, Golden, B.L, Gimble, F.S.
Deposit date:2010-08-31
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
3OOL
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BU of 3ool by Molmil
I-SceI complexed with C/G+4 DNA substrate
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ...
Authors:Joshi, R, Chen, J.-H, Golden, B.L, Gimble, F.S.
Deposit date:2010-08-31
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
3C0X
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BU of 3c0x by Molmil
I-SceI in complex with a top nicked DNA substrate
Descriptor: CALCIUM ION, DNA (5'-D(*DC*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DA)-3'), DNA (5'-D(*DG*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DCP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DT)-3'), ...
Authors:Moure, C.M, Gimble, F.S, Quiocho, F.A.
Deposit date:2008-01-21
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
3C0W
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BU of 3c0w by Molmil
I-SceI in complex with a bottom nicked DNA substrate
Descriptor: CALCIUM ION, DNA (5'-D(*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DGP*DTP*DAP*DAP*DTP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DT)-3'), ...
Authors:Moure, C.M, Gimble, F.S, Quiocho, F.A.
Deposit date:2008-01-21
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
1R7M
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BU of 1r7m by Molmil
The homing endonuclease I-SceI bound to its DNA recognition region
Descriptor: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ...
Authors:Moure, C.M, Gimble, F.S, Quiocho, F.A.
Deposit date:2003-10-21
Release date:2004-10-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
J.Mol.Biol., 334, 2003

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