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8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:dormant ribosome with eIF5A, eEF2 and SERBP1
To Be Published
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The global structure of dormant ribosome
To Be Published
8V9L
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BU of 8v9l by Molmil
Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ...
Authors:Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G.
Deposit date:2023-12-08
Release date:2024-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8QO9
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BU of 8qo9 by Molmil
Cryo-EM structure of a human spliceosomal B complex protomer
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2023-09-28
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (5.29 Å)
Cite:New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
8QHC
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BU of 8qhc by Molmil
Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX
Descriptor: E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Sharma, R, Adams, M, Bhogaraju, S.
Deposit date:2023-09-07
Release date:2023-10-11
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
8QFS
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BU of 8qfs by Molmil
Cryo-EM structure of SidH from Legionella pneumophila
Descriptor: Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sharma, R, Weis, F, Bhogaraju, S.
Deposit date:2023-09-04
Release date:2023-10-11
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
8Q7N
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BU of 8q7n by Molmil
cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2023-08-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8OZ0
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BU of 8oz0 by Molmil
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V.
Deposit date:2023-05-06
Release date:2024-02-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat.Struct.Mol.Biol., 31, 2024
8CMJ
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BU of 8cmj by Molmil
Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-20
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CKU
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BU of 8cku by Molmil
Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-16
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8G7P
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BU of 8g7p by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance
Nat.Struct.Mol.Biol., 2024
8G7Q
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BU of 8g7q by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance
Nat.Struct.Mol.Biol., 2024
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-15
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G60
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BU of 8g60 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8CIV
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BU of 8civ by Molmil
Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-10
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Cretu, C, Schmitzova, J, Pena, V.
Deposit date:2023-02-07
Release date:2023-05-10
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
8CG8
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BU of 8cg8 by Molmil
Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-03
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CF5
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BU of 8cf5 by Molmil
Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-02
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CEH
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BU of 8ceh by Molmil
Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-01
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.05 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CDR
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BU of 8cdr by Molmil
Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-31
Release date:2023-09-20
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Dybkov, O, Kastner, B, Luehrmann, R.
Deposit date:2023-01-12
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
Descriptor: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
Deposit date:2023-01-06
Release date:2023-09-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023

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PDB entries from 2024-03-27

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